Results 171 to 180 of about 2,525,099 (341)

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

From laboratory to market: the biotechnology industry in the Third District [PDF]

open access: yes
In "From Laboratory to Market: The Biotechnology Industry in the Third District," Tim Schiller describes major biotechnology products and reviews estimates of the industry's size and scope. He also outlines where the industry is most active in the United
Timothy Schiller
core  

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

ECONOMIC AND SOCIAL CONSEQUENCES OF BIOTECHNOLOGY: A SCENARIO ANALYSIS [PDF]

open access: yes
Over the years agricultural technology has created remarkable commodity production growth rates and enhanced general economic growth through food production, manufactured goods and trade for most nations.
Neven, David   +2 more
core   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

BIOREFINERIES AND BIOBASED PRODUCTS FROM THE CONSUMER'S POINT OF VIEW [PDF]

open access: yes
Paper prepared for presentation at the 13th ICABR International Conference on Agricultural Biotechnology: “The emerging bio-economy” Ravello (Italy), 18th to 20th June 2009Industrial biotechnology, Biorefinery, Consumer behaviour, Demand and Price ...
Kurka, Stefan, Menrad, Klaus
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

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