Results 41 to 50 of about 1,590,456 (297)
Biotechnology and society in Cuba: the case of the Molecular Immunology Center [PDF]
Trilogía Ciencia Tecnología Sociedad, 2014 since the 1980s, effective and sustained policies in the field of biotechnology have been pursued in Cuba. The highest priority has been given to the medical-pharmaceutical industry (medicine production, vaccines ...
Jorge Núñez Jover +1 more
doaj +1 more source
Biotechnology of Rhodococcus for the production of valuable compounds
Applied Microbiology and Biotechnology, 2020 Bacteria belonging to Rhodococcus genus represent ideal candidates for microbial biotechnology applications because of their metabolic versatility, ability to degrade a wide range of organic compounds, and resistance to various stress conditions, such as
M. Cappelletti +5 more
semanticscholar +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Current research in biotechnology: Exploring the biotech forefront
Current Research in Biotechnology, 2019 Biotechnology is an evolving research field that covers a broad range of topics. Here we aimed to evaluate the latest research literature, to identify prominent research themes, major contributors in terms of institutions, countries/regions, and journals.
Andy Wai Kan Yeung +36 more
doaj +1 more source
Proceedings of the workshop NANO23@uniVR - 8-9 June 2023, University of Verona, Italy
European Journal of Histochemistry, 2023 The workshop, organized by the PhD Course in Nanosciences and Advanced Technologies, aims to create a forum on hot topics of current interest in Nanoscience and Nanotechnology such as Nanomedicine, Biotechnology, Energy-nanotech, Environmental ...
The Scientific Committee
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
CO2 Capture Using Deep Eutectic Solvents Integrated with Microalgal Fixation
Clean Technologies, 2023 In this study, we investigated the use of functionalized deep eutectic solvents (DESs) as a medium for CO2 capture integrated with CO2 desorption and biofixation in microalgal culture, as an approach for carbon capture, utilization, and storage (CCUS ...
Eliza Gabriela Brettfeld +5 more
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source