Results 21 to 30 of about 127,266 (234)

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Analysis of Two Polyhydroxyalkanoate Synthases in Bradyrhizobium japonicum USDA 110 [PDF]

, 2013
Bradyrhizobium japonicum USDA 110 has five polyhydroxyalkanoate (PHA) synthases (PhaC) annotated in its genome: bll4360 (phaC1), bll6073 (phaC2), blr3732 (phaC3), blr2885 (phaC4), and bll4548 (phaC5).
Lodeiro, Anibal, Mongiardini, Elias Javier, Parisi, Gustavo Daniel, Pérez Giménez, Julieta, Quelas, Juan Ignacio   +4 more
core   +2 more sources

Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R‐Functionalized Magnetic Nanoparticles to Low‐Endocytic CCR9 Surface Receptors

Advanced Healthcare Materials, EarlyView.
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente, Isabel Corraliza‐Gorjón, Thomas S. van Zanten, María del Puerto Morales, Leonor Kremer, Domingo F. Barber   +5 more
wiley   +1 more source

Acute toxicity of arsenic and oxidative stress responses in the embryonic development of the common South American toad Rhinella arenarum [PDF]

, 2015
Arsenic (As), a natural element of ecological relevance, is found in natural water sources throughout Argentina in concentrations between 0.01mg/L and 15mg/L. The autochthonous toad Rhinella arenarum was selected to study the acute toxicity of As and the
Adams, Bagnyukova, Beers, Bongiovanni, Brix, Brodeur, Bundschuh, Chen, Del Conte, Ellman, Evelson, Farnfield, Ferrari, Ferrari, Ferrari, Guidi, Habig, Kensler, Kobayashi, Kono, Lascano, Lascano, Lowry, Lu, Miller, Montagna, Moriarty, Rahman, Rankin, Rizzo, Soria, Sotomayor, Suhendrayatna, Ventura-Lima, Ventura-Lima, Venturino, Venturino, White   +37 more
core   +1 more source

Machine Learning‐Assisted Infectious Disease Detection in Low‐Income Areas: Toward Rapid Triage of Dengue and Zika Virus Using Open‐Source Hardware

Advanced Intelligent Discovery, EarlyView.
This study introduces an affordable machine learning platform for simultaneous dengue and zika detection using fluorine‐doped tin oxide thin films modified with gold nanoparticles and DNA aptamers. Designed for low‐cost, hardware‐limited devices (< $25), the model achieves 95.3% accuracy and uses only 9.4 kB of RAM, demonstrating viability for resource‐
Marina Ribeiro Batistuti Sawazaki, Bassam Bachour Junior, Marcelo Mulato, José Ilton de Oliveira Filho   +3 more
wiley   +1 more source

A Multiepitope‐Based Lateral Flow Assay for Leprosy Antibodies

Analysis &Sensing, EarlyView.
An innovative lateral flow assay for leprosy diagnosis is based on gold nanoparticles and synthetic Mycobacterium leprae epitopes conjugated to keyhole limpet hemocyanin protein to enhance antibody detection. This strategy provides a rapid, accurate, and low‐cost approach for resource‐limited settings, enabling the early detection of infection. Leprosy
Cristiane Zocatelli‐Ribeiro, Camila dos Anjos Proença, Ana Carolina da Rosa Nogarolli, Ana Fabiele Domakoski Trevisan, Thiago Neves Machado, João Carlos Degraf Muzzi, Larissa Magalhães Alvarenga, Juliana de Moura   +7 more
wiley   +1 more source

DNA metabarcoding reveals greater plant diversity than morphological seed analysis of bird feces

Applications in Plant Sciences, EarlyView.
Abstract Premise Fruit‐eating birds drive seed dispersal in recovering tropical ecosystems, shaping forest regeneration. Molecular techniques, such as DNA metabarcoding, enable diet analysis from feces and can provide complementary frugivory data where dispersal is infrequent, as well as aid in seed identification in hyper‐diverse regions lacking ...
Carina I. Motta, Bruno H. Saranholi, Vinicius Marciano De Godoy, Marina Corrêa Côrtes   +3 more
wiley   +1 more source

Mención de honor del Premio Nacional de Ciencia 2014 otorgada por el Congreso Nacional “Innovación diagnóstica aplicada a casos de infecciones respiratorias agudas graves en niños menores de 5 años hospitalizados revela alta incidencia de co-infecciones

Memorias del Instituto de Investigaciones en Ciencias de la Salud, 2015
—
Biología Molecular y Biotecnología IICS
doaj  

Antagonistic capacities of Trichoderma species and their mass multiplication with agricultural wastes [PDF]

, 2018
El objetivo de esta investigación fue aislar y caracterizar cepas de Trichoderma nativas de Misiones (Argentina)explorando sus capacidades antagónicas y su multiplicación masiva utilizando diferentes residuos agroindustriales.Quince cepas nativas de ...
Castrillo, María Lorena, Gutierrez Brower, Gimena, Lopez, Ana Clara, Ojeda, Paola, Otegui, Monica Beatriz, Sadañoski, Marcela Alejandra, Villalba, Laura Lidia, Zapata, Pedro Dario   +7 more
core  

KH2PO4 improves cellulase production of Irpex lacteus and Pycnoporus sanguineus [PDF]

, 2018
The optimization of cellulase production by Irpex lacteus and Pycnoporus sanguineus was investigated. Fractional factorial design was conducted to determine significant variables and interactions.
Alonso Paiva, Iván Mathias, Castrillo, María Lorena, Rodríguez, María Daniela, Villalba, Laura Lidia, Zapata, Pedro Dario   +4 more
core   +1 more source