Results 91 to 100 of about 381,611 (334)

Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph   +5 more
wiley   +1 more source

Intestinal Dysbiosis and Biotin Deprivation Induce Alopecia through Overgrowth of Lactobacillus murinus in Mice.

open access: yesCell Reports, 2017
Metabolism by the gut microbiota affects host physiology beyond the gastrointestinal tract. Here, we find that antibiotic-induced dysbiosis, in particular, overgrowth of Lactobacillus murinus (L.
A. Hayashi   +14 more
semanticscholar   +1 more source

The use of non-radioactive iodine as a label in immunoassays [PDF]

open access: yes, 1995
The research described in this thesis has centered on the development of a nonradioactive iodine label for use in immunoassays. A protein can be iodinated with nonradioactive iodine, used in an immunoassay, and the iodine label detected by a chemical ...
Butler, Mary
core   +2 more sources

DNA‐Templated 2D Heterostructures as Phototriggered Dynamic Nanohybrids: From Releasing Molecular Loads to Controlling Enzyme Biocatalytic Function

open access: yesAdvanced Functional Materials, EarlyView.
DNA strands are employed both as dynamic linkers and nanoscale templates for the integration of Ag2S nanoparticles on MoS2, which in turn imparted photothermal responsiveness; this feature permits the selective cargo (fluorophore, quantum dots or an enzyme) release from the MoS2 surface in response to local heat induced by light irradiation.
Kai Chen   +3 more
wiley   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

Molecular Recognition Studies on Naphthyridine Derivatives

open access: yesMolecules, 2010
The association constants Kb of three hosts I–III designed to have both enhanced hydrogen bonding donor strength and conformational preorganization with biotin analogues 1–5 are reported.
José Carlos Iglesias-Sánchez   +3 more
doaj   +1 more source

Testing the Specificity and Cytotoxicity of Biotin-Ferrocene Compounds on Cancer Cells

open access: yes, 2017
Cancer cells are characterized by loss of regulation of the cell cycle that results in uncontrolled proliferation. To drive this high rate of cellular division, cancer cells have mutated to increase uptake of vitamins by increasing the number of vitamin ...
Reid, Eric
core  

Polyethylene imine-based receptor immobilization for label free bioassays [PDF]

open access: yes, 2013
Polyethylene imine (PEI) based immobilization of antibodies is described and the concept is proved on the label free assay of C-Reactive Protein (CRP).
Orgovan, Norbert   +7 more
core   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

open access: yesAdvanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake   +5 more
wiley   +1 more source

A HABA dye-based colorimetric assay to detect unoccupied biotin binding sites in an avidin-containing fusion protein

open access: yesBioTechniques
Avidin-biotin binding, the most robust non-covalent protein-ligand interaction occurring in nature, has wide-ranging applications in biotechnology. A frequent challenge in these applications is accurately determining the number of unoccupied biotin ...
Sonia Mukherjee   +3 more
doaj   +1 more source

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