Results 91 to 100 of about 456,411 (294)

Bifunctional Surfaces With Immobilized Antibodies and Bioactive Peptides Mediate Selective Capture and Proliferation of Endothelial Colony‐Forming Cells

Advanced Healthcare Materials, EarlyView.
A tunable bifunctional surface is developed by combining Fc‐binding peptides and RGD motifs to present oriented antibodies alongside integrin‐mediated signaling. The platform selectively captures endothelial colony‐forming cells while promoting their adhesion and proliferation.
Hugo A. Level, Marc‐Antoine Campeau, Mohamed A. Elkhodiry, Gaétan Laroche, Jean‐François Tanguay, Corinne A. Hoesli   +5 more
wiley   +1 more source

6-(7,8-Dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)hexyl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate

Molbank
Herein we report the synthesis of 6-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)hexyl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate.
Simona Marincean, Diana Nichols, Rachael Schulz, Travis Branscum, Marilee Benore   +4 more
doaj   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

A Systems Hypothesis of Lipopolysaccharide-Induced Vitamin Transport Suppression and Metabolic Reprogramming in Autism Spectrum Disorders: An Open Call for Validation and Therapeutic Translation

Metabolites
Background: Autism spectrum disorder (ASD) is increasingly linked to systemic metabolic dysfunction, potentially influenced by gut–brain axis dysregulation, but the underlying mechanisms remain unclear. Methods: We developed Personalized Metabolic Margin
Albion Dervishi
doaj   +1 more source

Structure of Supramers Formed by the Amphiphile Biotin‐CMG‐DOPE

ChemistryOpen, 2020
The synthetic function‐spacer‐lipid (FSL) amphiphile biotin‐CMG‐DOPE is widely used for delicate ligation of living cells with biotin residues under physiological conditions.
Anton Zalygin, Daria Solovyeva, Ivan Vaskan, Dr. Stephen Henry, Dr. Marcel Schaefer, Dr. Pavel Volynsky, Dr. Alexander Tuzikov, Dr. Elena Korchagina, Dr. Ivan Ryzhov, Dr. Alexey Nizovtsev, Dr. Konstantin Mochalov, Prof. Roman Efremov, Dr. Eleonora Shtykova, Dr. Vladimir Oleinikov, Prof. Nicolai Bovin   +14 more
doaj   +1 more source

Giant Magnetoresistive Biosensors for Time-Domain Magnetorelaxometry: A Theoretical Investigation and Progress Toward an Immunoassay. [PDF]

, 2017
Magnetorelaxometry (MRX) is a promising new biosensing technique for point-of-care diagnostics. Historically, magnetic sensors have been primarily used to monitor the stray field of magnetic nanoparticles bound to analytes of interest for immunoassays ...
Hall, Drew A, Huang, Chih-Cheng, Zhou, Xiahan   +2 more
core   +1 more source

Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells

Advanced Materials, EarlyView.
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno, Qiangrui Dong, Marco Post, Xin Meng, Cristiano Glessi, Nynke Marije Hettema, Nidas Brandsma, Sebbe Blokhuizen, Alejandro Castañeda Garcia, Srividya Ganapathy, Thieme Schmidt, Lars van Roemburg, Bing Xu, Chun‐Ting Cho, Liedewij Laan, Miao‐Ping Chien, Daan Brinks   +16 more
wiley   +1 more source

Biotinidase Deficiency: Prevalence, Impact And Management Strategies

Pediatric Health, Medicine and Therapeutics, 2020
Ebru Canda, Sema Kalkan Uçar, Mahmut Çoker Department of Pediatrics, Faculty of Medicine, Ege University, Izmir, TurkeyCorrespondence: Ebru CandaDepartment of Pediatrics, Faculty of Medicine, Ege University, Izmir 35040, TurkeyTel + 90 232 ...
Canda E, Kalkan Uçar S, Çoker M
doaj  

Structural Characterization of the Avidin Interactions with Fluorescent Pyrene-Conjugates: 1-Biotinylpyrene and 1-Desthiobiotinylpyrene

Molecules, 2016
Avidin is a tetrameric protein that belongs to the calycin superfamily. It has been studied mainly because of its extraordinary affinity to biotin, which led to a wide range of applications based on the avidin-biotin system.
Paweł Strzelczyk, Damian Plażuk, Janusz Zakrzewski, Grzegorz Bujacz   +3 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source