The single‐molecule with a large transistor‐SiMoT is proposed for the detection of the subgenomic RNA of SARS‐CoV‐2, achieving a diagnostic sensitivity of 98.0% and a specificity of 87.8%. The SiMoT technology, currently at TRL‐5, is suitable for point‐of‐care settings and delivers the result to the end user in 30 min.
Eleonora Macchia+12 more
wiley +1 more source
Virus Detection by CRISPR-Cas9-Mediated Strand Displacement in a Lateral Flow Assay. [PDF]
Montagud-Martínez R+7 more
europepmc +1 more source
Studies on Production of Biotin by Microorganisms
Toshimichi Tsuboi+2 more
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Cell Membrane‐Coated Lipid Nanoparticles for Drug Delivery
This review highlights recent progress in cell membrane‐coated lipid nanoparticles (CMC‐LNPs), focusing on their design, preparation methods, functional integration, and biomedical applications. It discusses various types of LNPs and coating strategies, characterization techniques, therapeutic functions, and applications.
Moataz B. Zewail+5 more
wiley +1 more source
Methodology and application of multiplex PCR-dipstick DNA chromatography for the detection of eight respiratory bacterial pathogens. [PDF]
Hu L, Wang X, Li Q.
europepmc +1 more source
EFFECT OF PENICILLIN ON THE PRODUCTION OF GLUTAMIC ACID BY NON-BIOTIN-REQUIRING BACTERIA
SHIN-ICHIRÔ ÔTSUKA+3 more
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Prenatal Brain Abnormalities in Sodium‐Dependent Multivitamin Transporter Deficiency
ABSTRACT In treatable neurometabolic disorders, early diagnosis and prompt initiation of treatment are key to improved survival and outcomes. Biallelic variants in SLC5A6 cause sodium‐dependent multivitamin transporter deficiency (OMIM # 618973), which is treatable with high‐dose pantothenic acid, biotin, and alpha lipoic acid.
Eri Ogawa+2 more
wiley +1 more source
Holocarboxylase Synthetase Deficiency: Clinical, Biochemical and Molecular Findings in Five Malaysian Patients Including a Newborn Presenting as Collodion Baby. [PDF]
Ting SL+4 more
europepmc +1 more source
STUDIES ON THE FORMATION OF BIOTIN FROM DESTHIORIOTIN AND SULFATE IN SACCHAROMYCES CEREVISIAE
Toshio Niimura+2 more
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ABSTRACT The MT‐ATP6 gene m.8993T>G pathogenic variant has been associated with Leigh syndrome, especially in patients exhibiting a high degree of heteroplasmy. Although patients may present with a wide phenotypic spectrum, characteristic findings include bilateral, symmetric hyperintensities in the basal ganglia and brainstem on brain MRI ...
Ramya Treitel+2 more
wiley +1 more source