Results 141 to 150 of about 62,756 (305)

Microbiome‐mediated chemical communication in insects: Implications for pest management

Pest Management Science, EarlyView.
Microbiome–semiochemical interactions involve the following processes: direct microbial synthesis, host gene regulation, precursor biotransformation, microbiome modulation and indirect ecological signaling. Abstract Insects rely on semiochemicals to regulate aggregation, mating, foraging, and host selection. This review synthesizes evidence that insect‐
Ioannis Eleftherianos, Wei Zhang, Amr Mohamed, Rasha K. Al‐Akeel, Abeer M. Alkhaibari, Nemat Keyhani, Guy Smagghe   +6 more
wiley   +1 more source

Influence of dioxin and metal-contaminated sediment on phase I and II biotransformation enzymes in silver crucian carp

, 1998
Several biochemical responses were measured in silver crucian carp (Carassius auratus gibelio) after exposure to sediments obtained from contaminated Ya-Er Lake, No, 1 pond, and an unpolluted reference site, Honglian Lake.
Chen Guosheng, Xu Ying, Chen, GS, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China, Karl-Werner Schramm and Antonius Kettrup, Zhang Yongyuan, Xu Lihong   +5 more
core  

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo, Woojin Jung, Tham Thi Bui, Hwi‐yeol Yun, Jung‐woo Chae, Jeremiah D. Momper   +5 more
wiley   +1 more source

Phytochemicals in MASLD: A Focused Review of Gut Microbiome‐Linked Mechanisms

Phytotherapy Research, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as a major global health burden, yet effective pharmacological options remain limited. Recent advances highlight the gut microbiome as a key modulator of liver metabolism, inflammation, and fibrosis, making it a promising therapeutic target.
Jeong In Seo, Su Min Kim, Hye Hyun Yoo
wiley   +1 more source

Organic and Inorganic Pollutants, Oxidative Stress Biomarkers, and Electrophoretic Protein Profiles in an Endangered Thresher Shark (Alopias vulpinus) From Southeastern Brazil: A Case Study

Environmental Toxicology, EarlyView.
ABSTRACT A comprehensive screening of different environmental contaminants (total metals, thermostable metal fractions associated with detoxification, and persistent organic pollutants) was conducted in an endangered common thresher shark (Alopias vulpinus ) individual incidentally captured in southeastern Brazil.
Sidney Fernandes Sales Junior, Amanda Pontes Lopes, Heloíse Martins de Souza, Regina Fonseca, Enrico Mendes Saggioro, Francielli Monteiro Casanova, Kamila Cezar Gramlich, Tatiana Dillenburg Saint'Pierre, Carlos German Massone, Renato Carreira, Rachel Ann Hauser‐Davis   +10 more
wiley   +1 more source

Cytotoxic and Apoptotic Effects of 17α-Ethynylestradiol and Diethylstilbestrol on CHO-K1 Cells

Food Technology and Biotechnology, 2011
There is considerable concern about the substances present in the environment and their potential to interfere with the endocrine system of vertebrates.
Višnja Gaurina Srček, Zlatko Kniewald, Mirna Mihajlović, Igor Slivac, Kristina Radošević, Jerka Dumić, Ruđer Novak   +6 more
doaj  

Untreated Hair Dye Effluents Enter the Environment: Are They a Threat to Human Health?

Environmental Toxicology, EarlyView.
ABSTRACT The effluents generated during the process of hair dyeing exhibit a complex composition, comprising chemical compounds with varying toxicity levels. While the adverse impact of hair dyes on human health is acknowledged, there is a notable absence of studies addressing the toxicity associated with effluents produced during these activities. The
Letícia Cristina Gonçalves, Matheus Mantuanelli Roberto, Adriana Fabiana Corrêa da Silva, Maria Aparecida Marin‐Morales   +3 more
wiley   +1 more source

Isotopic Fractionation and Masking Effects during Biotransformation of Chlorinated Ethanes. [PDF]

Environ Sci Technol
Phillips E, De Vera J, Kümmel S, Bulka O, Chen W, Edwards E, Nijenhuis I, Gehre M, Sherwood Lollar B.   +8 more
europepmc   +1 more source