Results 81 to 90 of about 57,036 (277)

Identification of Metabolites of the Dietary Supplement Ingredient 5α‐Hydroxy‐Laxogenin

Drug Testing and Analysis, EarlyView.
The biotransformation of the dietary supplement ingredient 5α‐hydroxy‐laxogenin was investigated using human HepG2 cells, the rat and in silico using the online software Next‐gen E‐Resource for Drug Discovery (NERDD). We identified five metabolites generated by the human HepG2 cells of which three and an additional mono‐hydroxylated metabolite were ...
Daniel Derwand, Oliver Zierau, Detlef Thieme, Annekathrin Martina Keiler   +3 more
wiley   +1 more source

Cordyceps sinensis-mediated biotransformation of notoginsenoside R1 into 25-OH-20(S/R)-R2 with elevated cardioprotective effect against DOX-induced cell injury

, 2022
Jishuang Liu, Yu Xin, Zhidong Qiu, Qi Zhang, Tianzhu He, Ye Qiu, Wei‐Nan Wang   +6 more
openalex   +2 more sources

Covalent Immobilization of Laccase on Mesoporous Bismuth Silicate for High‐Performance Biodegradation of Contaminants

European Journal of Inorganic Chemistry, EarlyView.
Myceliophthora thermophila laccase covalently immobilized on bismuth silicate (BiSi‐ext) achieved synergistic adsorption–biodegradation of Tectilon Blue 4R‐01 and ibuprofen. The biocatalyst showed enhanced stability, reusability, and rapid pollutant removal via expanded active‐site accessibility, enabling efficient, eco‐friendly wastewater remediation.
Erick Paiva Cancella, Guilherme de Paula Guarnieri, Yuriy B. Lipisa, Fábio Rogério de Moraes, Adriano de Vasconcellos, Giselle Maria Maciel, José Geraldo Nery   +6 more
wiley   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Paraverrucsins A–F, Antifeedant, and Antiphytopathogenic Polyketides from Rhizospheric Paraphaeosphaeria verruculosa and Induced Bioactivity Enhancement by Coculturing with Host Plant Dendrobium officinale

ACS Omega, 2020
Ming Hu, Xue-Qiong Yang, Cui-Fang Wang, Tong-De Zhao, Dai-Li Wang, Ya-Bin Yang, Zhong-Tao Ding   +6 more
doaj   +1 more source

Standardization and micromechanistic study of tetracycline adsorption by biochar

Biochar
Modification serves as an excellent approach to  enhancing the adsorption performance of biochar for tetracycline. Selective modification further allows the attainment of biochar materials that are not only more efficient but also cost-effective. However,
Xiaotong Zhang, Jinju Hou, Shudong Zhang, Tong Cai, Shujia Liu, Wenjin Hu, Qiuzhuo Zhang   +6 more
doaj   +1 more source

Biotransformation of Hydroxychalcones as a Method of Obtaining Novel and Unpredictable Products Using Whole Cells of Bacteria [PDF]

, 2020
Joanna Kozłowska, Bartłomiej Potaniec, Mirosław Anioł   +2 more
openalex   +1 more source

Cytotoxicity of 19 Pesticides in Rainbow Trout Gill, Liver, and Intestinal Cell Lines

Environmental Toxicology and Chemistry, EarlyView.
Abstract The rainbow trout gill cell line (RTgill‐W1), via test guideline 249 of the Organisation for Economic Co‐operation and Development, has been established as a promising New Approach Methodology, although to advance confidence in the method more case studies are needed that: 1) expand our understanding of applicability domains (chemicals with ...
Sophie Emberley‐Korkmaz, Krittika Mittal, Na'im Temlock, Jessica Head, Niladri Basu   +4 more
wiley   +1 more source

Biotransformation of anthelmintics in nematodes in relation to drug resistance

International Journal for Parasitology: Drugs and Drug Resistance
In all organisms, the biotransformation of xenobiotics to less toxic and more hydrophilic compounds represents an effective defense strategy. In pathogens, the biotransformation of drugs (used for their elimination from the host) may provide undesirable ...
Ondřej Vosála, Josef Krátký, Petra Matoušková, Nikola Rychlá, Karolína Štěrbová, Lucie Raisová Stuchlíková, Ivan Vokřál, Lenka Skálová   +7 more
doaj   +1 more source

Biotransformation and Kinetics of Excretion of Ethyl tert-Butyl Ether in Rats and Humans [PDF]

, 2000
Alexander Amberg
openalex   +1 more source