Results 231 to 240 of about 7,408 (290)
Some of the next articles are maybe not open access.
Biotransformations of Explosives
Biotechnology and Genetic Engineering Reviews, 2001(2001). Biotransformations of Explosives. Biotechnology and Genetic Engineering Reviews: Vol. 18, No. 1, pp. 171-217.
C E, French, S J, Rosser, N C, Bruce
openaire +2 more sources
Clinical Pharmacology and Therapeutics, 1982
Two healthy subjects took 3H-digoxigenin-12 alpha and unlabeled digoxigenin. Metabolites were assayed by high-pressure liquid chromatography (HPLC) in serum and urine. Of the tritium activity in the serum at 30 min, less than 26% chromatographed with digoxigenin; the rest chromatographed as metabolites, most of which were polar.
H, Gault +3 more
openaire +2 more sources
Two healthy subjects took 3H-digoxigenin-12 alpha and unlabeled digoxigenin. Metabolites were assayed by high-pressure liquid chromatography (HPLC) in serum and urine. Of the tritium activity in the serum at 30 min, less than 26% chromatographed with digoxigenin; the rest chromatographed as metabolites, most of which were polar.
H, Gault +3 more
openaire +2 more sources
Biotransformations with nitrilases
Current Opinion in Chemical Biology, 2010The range of possible nitrilase applications has been recently broadened but in most cases the parameters of the reactions need to be improved to establish viable industrial processes. To achieve this goal, several methods have been used, primarily in screening for enzymes from new sources, enzyme improvement, substrate structure modification, medium ...
Ludmila, Martínková, Vladimír, Kren
openaire +2 more sources
Biotechnology Advances, 2006
The main application of terpenes as fragrances and flavors depends on the absolute configuration of the compounds because enantiomers present different organoleptic properties. Biotransformations allow the production of regio- and stereoselective compounds under mild conditions. These products may be labeled as "natural".
Carla C C R, de Carvalho +1 more
openaire +2 more sources
The main application of terpenes as fragrances and flavors depends on the absolute configuration of the compounds because enantiomers present different organoleptic properties. Biotransformations allow the production of regio- and stereoselective compounds under mild conditions. These products may be labeled as "natural".
Carla C C R, de Carvalho +1 more
openaire +2 more sources
Biotransformation of Neuropeptides
Neuroendocrinology, 2008The ability of neuropeptides to act as precursors for smaller, biologically active fragments is discussed in terms of their biotransformation. This process may involve cleavage of the parent peptide by peptidase enzymes to produce shorter polypeptides with defined biological activity, though other enzymic processes such as sulphation and acetylation ...
E C, Griffths, J R, McDermott
openaire +2 more sources
Clinical Pharmacology and Therapeutics, 1984
Serum digoxin and metabolites were assayed in plasma and urine by HPLC in 10 dialysis-dependent patients with end-stage renal failure (group I) and in five patients with comparatively normal renal function (group II) after ingestion of 150 muCi 3H-digoxin-12 alpha.
M H, Gault +6 more
openaire +2 more sources
Serum digoxin and metabolites were assayed in plasma and urine by HPLC in 10 dialysis-dependent patients with end-stage renal failure (group I) and in five patients with comparatively normal renal function (group II) after ingestion of 150 muCi 3H-digoxin-12 alpha.
M H, Gault +6 more
openaire +2 more sources
1978
During the past several years it has become generally accepted that the incidence of adverse reactions to drugs in patients increase with age (1–3). However, the reasons for the increased incidence are frequently obscure and often differ with the drug.
J R, Gillette, J A, Hinson
openaire +2 more sources
During the past several years it has become generally accepted that the incidence of adverse reactions to drugs in patients increase with age (1–3). However, the reasons for the increased incidence are frequently obscure and often differ with the drug.
J R, Gillette, J A, Hinson
openaire +2 more sources
Biotransformation of Phencyclidine
Drug Metabolism Reviews, 1985PCP is metabolized extensively in the body via a variety of metabolic routes. Biotransformation is a major mechanism of PCP elimination in humans and termination of PCP action in mice. In general, PCP metabolites are less active pharmacologically than PCP itself.
E J, Holsztynska, E F, Domino
openaire +2 more sources
Biotransformation of Sevoflurane
Anesthesia & Analgesia, 1995Several characteristics of sevoflurane biotransformation are apparent from the preceding investigations. Metabolism is rapid, with fluoride and HFIP appearing in plasma within minutes after the start of sevoflurane administration (38-40,51). Peak plasma fluoride concentrations generally occur within approximately 1 h after the termination of ...
openaire +2 more sources
Toxicologic Pathology, 1988
About 4 million compounds have been described by chemists, and some 60,000 are presently on the market. The search for new chemicals with better properties and less toxicity continues, and future life quality will depend on our ability to find the safest compounds in each field of application.
openaire +2 more sources
About 4 million compounds have been described by chemists, and some 60,000 are presently on the market. The search for new chemicals with better properties and less toxicity continues, and future life quality will depend on our ability to find the safest compounds in each field of application.
openaire +2 more sources