Results 161 to 170 of about 1,636,826 (281)

FeIII‐Mediated Synthesis of Azaspirodienones via Ipso‐Radical Cyclization of Ugi–4CR Adducts

European Journal of Organic Chemistry, EarlyView.
An efficient two‐step protocol for the synthesis of azaspirodienones via Fe‐mediated ipso‐radical cyclization of Ugi adducts has been developed. This methodology provides rapid access to these privileged spirocyclic architectures under mild conditions, offering a practical and versatile approach to generating structurally complex molecules with ...
Silvia J. Becerra–Anaya, Valeria Morales–Hernández, Luis A. Polindara–García   +2 more
wiley   +1 more source

pH-Regulated Reversible Phase Transition of Natural Deep Eutectic Solvents and Its Application in the Extraction of Fluorinated Liquid Crystal Monomers. [PDF]

J Sep Sci
Shao Y, Jiang X, Jin M, Yang X, Li Z, Liu J.   +5 more
europepmc   +1 more source

Fluorene‐based blue emitters: On the path to electrically pumped organic lasers

FlexMat, EarlyView.
Electrically pumped efficient operation remains unrealized, a major challenge in optoelectronics. Fluorene‐based blue‐emitting semiconductors are promising gain media, thanks to their structural tunability and favorable emission properties. This review summarizes recent advances, highlights their reliability and versatility in lasing, and outlines key ...
Yong Yan, Hao Li, Mengna Yu, Huiyin Wang, Jiangqiang He, Menghan Wu, Quanyou Feng, Linghai Xie   +7 more
wiley   +1 more source

Selective Brain-Penetrant TTBK1 Inhibitors Modulate TDP-43 Pathology and Rescue Cognitive Deficits in a Mouse Model of TDP-43 Proteinopathy. [PDF]

J Med Chem
Sanchez-Santos C, Jimenez-Amor A, Martinez-Gonzalez L, Nozal V, Martin-Morales R, Aledavood E, Bausela D, Merrigan K, Diaz-Palacios K, Zhubi R, Knapp S, Garcia-Gonzalo FR, Rodriguez-Cueto C, Gil C, de Lago E, Martinez A.   +15 more
europepmc   +1 more source

Highly efficient blue crystalline organic light‐emitting diodes enabled by a hot exciton sensitizer PyPO

FlexMat, EarlyView.
Two different sensitization structures (hot exciton sensitizer type and exciton nanoaggregate type) were integrated into crystalline host matrix. The resulting crystalline organic light‐emitting diodes exhibit low Joule heat loss ratio and high photon output.
Hao Hu, Bo Yu, Ping Lu, Feng Zhu, Donghang Yan   +4 more
wiley   +1 more source

Pyrimidine-based NNRTIs in HIV therapy: advances in synthesis, potency and structure-activity relationships. [PDF]

RSC Adv
Ali H, Hashmi MA, Ajmal N, Goraija MS, Rasool N, Siddiqua UH, Malik A.   +6 more
europepmc   +1 more source

Recent advances and prospects for high‐efficiency blue hot exciton organic light‐emitting diodes

FlexMat, EarlyView.
Blue organic light‐emitting diodes (OLEDs) face great challenges in achieving the balance between color purity, device efficiency, and stability. Hot exciton materials offer a solution by rapidly converting non‐emissive triplet excitons into singlet ones through a high‐lying reverse intersystem crossing process.
Xiaoen Shi, Shuyuan Ge, Futong Liu, Ping Lu   +3 more
wiley   +1 more source

Multiscale Explainable Machine Learning Reveals Descriptor-Invariant Molecular Determinants of Small-Molecule PD-1/PD-L1 Inhibition. [PDF]

ACS Med Chem Lett
Manan A, Ilyas S.
europepmc   +1 more source

Food Contamination and Safety in Nigeria: A Systematic Synthesis of Heavy Metals, Microbial Pathogens, and Health Risk Metrics

Food Safety and Health, EarlyView.
This is an infographic driver of food contaminants and health effects. ABSTRACT Food safety remains a critical challenge in Nigeria due to rapid urbanization and weak regulatory enforcement. This systematic review synthesizes empirical evidence from 2015 to 2025 to characterize food contaminant profiles and associated human health risks in Nigeria ...
Cecilia Nwadiuto Obasi, Naomi A. Mogborukor, Baridoo Donatus Dooka, Polycarp Dauda Madaki, Chiara Frazzoli, Mohamed Haddad, Orish Ebere Orisakwe   +6 more
wiley   +1 more source

Aryl radical addition-dehydrocyclization drives rapid polycyclic aromatic hydrocarbon growth. [PDF]

Nat Commun
Goettl SJ, Sun BJ, Turner AM, Drissi M, Garcia GA, Nahon L, Kadam KP, Chang AHH, Kaiser RI.   +8 more
europepmc   +1 more source