Results 11 to 20 of about 47,366 (291)

Identification of 2,4‐Dinitro‐Biphenyl‐Based Compounds as MAPEG Inhibitors [PDF]

ChemMedChem, 2022
AbstractWe identified 2,4‐dinitro‐biphenyl‐based compounds as new inhibitors of leukotriene C4 synthase (LTC4S) and 5‐lipoxygenase‐activating protein (FLAP), both members of the “Membrane Associated Proteins in Eicosanoid and Glutathione metabolism” (MAPEG) family involved in the biosynthesis of pro‐inflammatory eicosanoids.
Di Micco, Simone, Terracciano, Stefania, Pierri, Martina, Cantone, Vincenza, Liening, Stefanie, König, Stefanie, Garscha, Ulrike, Hofstetter, Robert Klaus, Koeberle, Andreas, Werz, Oliver, Bruno, Ines, Bifulco, Giuseppe   +11 more
openaire   +4 more sources

ADMET polymerization of bio-based biphenyl compounds [PDF]

Polymer Chemistry, 2015
Bio-based phenols were dimerized and employed as monomers in ADMET polymerization.
A. Llevot, E. Grau, S. Carlotti, S. Grelier, H. Cramail   +4 more
openaire   +2 more sources

Dehalogenation, Denitration, Dehydroxylation, and Angular Attack on Substituted Biphenyls and Related Compounds by a Biphenyl Dioxygenase [PDF]

Journal of Bacteriology, 2001
ABSTRACT The attack by the bph -encoded biphenyl dioxygenase of Burkholderia sp. strain LB400 on a number of symmetrical ortho -substituted biphenyls or quasi ortho -substituted biphenyl analogues has been investigated. 2,2′-Difluoro-,
M, Seeger, B, Cámara, B, Hofer
openaire   +3 more sources

Comparison crystal structure conformations of two structurally related biphenyl analogues: 4,4′-bis[3-(pyrrolidin-1-yl)prop-1-yn-1-yl]-1,1′-biphenyl and 4,4′-bis{3-[(S)-2-methylpyrrolidin-1-yl]prop-1-yn-1-yl}-1,1′-biphenyl

Acta Crystallographica Section E: Crystallographic Communications, 2015
The title compounds, C26H28N2, (I), and C28H32N2, (II), were designed based on the structure of the potent α9α10 nicotinic acetylcholine receptor antagonist ZZ161C {1,1′-[[1,1′-biphenyl]-4,4′-diylbis(prop-2-yne-3,1-diyl)]bis(3,4-dimethylpyridin-1-ium ...
Anqi Wan, Narsimha Reddy Penthala, E. Kim Fifer, Sean Parkin, Peter A. Crooks   +4 more
doaj   +3 more sources

Novel Fluorinated Biphenyl Compounds Synthesized via Pd(0)-Catalyzed Reactions: Experimental and Computational Studies. [PDF]

ACS Omega, 2023
Five new difluorinated biphenyl compounds, 4′-(tert-butyl)-3,4-difluoro-1,1′-biphenyl (TBDFBP), 1-(3′,4′-difluoro-[1,1′-biphenyl]-4-yl)ethanone (DFBPE), 3′,4′-difluoro-2,5-dimethoxy-1,1′-biphenyl (DFDMBP), 3,4-difluoro-3′-nitro-1,1′-biphenyl (DFNBP), and
Rehman MAU, Adeel M, Alshehri SM, Aiman U, Villinger A, Bullo S, Baby R, Asghar MA, Kuznetsov AE, Sanyang ML.   +9 more
europepmc   +2 more sources

Evaluation of the In Vitro Antifungal Activity of Novel Arylsulfonamides against Candida spp.

Microorganisms, 2023
The antifungal activity of molecules belonging to the arylsulfonamide chemotype has previously been demonstrated. Here, we screened arylsulfonamide-type compounds against a range of Candida spp. and further established the structure–activity relationship
Giovanna Ginestra, Teresa Gervasi, Francesca Mancuso, Federica Bucolo, Laura De Luca, Rosaria Gitto, Davide Barreca, Giuseppina Mandalari   +7 more
doaj   +1 more source

Studies on bioactive bis-1,3,5-triazinyl dithiocarbamates [PDF]

Journal of the Serbian Chemical Society, 2007
The compounds bis(4,6-dichloro/bis[(p-methoxyphenyl)amino]-1,3,5- -triazin-2-yl)1,2-hydrazine-1,2-dicarbodithioate/1,4-phenylenebis(carbamodithioate)/( 1,1’-biphenyl)-4,4’-diylbis(carbamodithioate)/(sulphonyldi-4,1-phenylene)- bis(carbamodithioate/1,2 ...
Lunagariya V.D., Desai R.M., Shah V.H.
doaj   +3 more sources

Placental transfer of a hydroxylated polychlorinated biphenyl and effects on fetal and maternal thyroid hormone homeostasis in the rat [PDF]

, 2002
Earlier studies at our laboratory indicated that several hydroxylated polychlorinated biphenyls (OH-PCBs) detected in human blood could specifically inhibit thyroxine (T4) transport by competitive binding to the thyroid hormone transport protein ...
Bergman, A., Berg, J.J.J., van den, van den Berg, J.H.J., Meerts, I.A.T.M., Weijers, B.M., van den Berg, J.J.J., Brouwer, A., Assink, Y., Cenijn, P.H., Berg, J.H.J. van den, Koeman, J.H., Assin, Y.   +11 more
core   +1 more source

Synthesis of inventive biphenyl and azabiphenyl derivatives as potential insecticidal agents against the cotton leafworm, Spodoptera littoralis

BMC Chemistry, 2023
The emergence of pest resistance of Spodoptera littoralis (order; Lepidoptera, family; Noctuidae) towards the large scale of different classes of insecticides necessitates the development of some new poly-functionalized biphenyl and azabiphenyl with ...
Eslam A. Ghaith, Hajar A. Ali, Mohamed A. Ismail, Abd El-Aziz S. Fouda, M. Abd El Salam   +4 more
doaj   +1 more source

Novel biphenyl ester derivatives as tyrosinase inhibitors: Synthesis, crystallographic, spectral analysis and molecular docking studies.

PLoS ONE, 2017
Biphenyl-based compounds are clinically important for the treatments of hypertension and inflammatory, while many more are under development for pharmaceutical uses. In the present study, a series of 2-([1,1'-biphenyl]-4-yl)-2-oxoethyl benzoates, 2(a-q),
Huey Chong Kwong, C S Chidan Kumar, Siau Hui Mah, Tze Shyang Chia, Ching Kheng Quah, Zi Han Loh, Siddegowda Chandraju, Gin Keat Lim   +7 more
doaj   +1 more source