Results 301 to 310 of about 3,167,039 (375)

Mirex-induced suppression of biliary excretion of polychlorinated biphenyl compounds

Toxicology and Applied Pharmacology, 1976
Abstract Isolated perfused rat liver preparations were utilized to study the drug-induced modification of biliary excretion of [ 14 C]4-chlorobiphenyl (1-CB) and [ 14 C]2,4,5-2′,4′,5′-hexachlorobiphenyl (6-CB) and their metabolites. The effect of pretreatment of rats with mirex was compared with that of phenobarbital (PB) and 6-CB by measuring the ...
H. Mehendale
openaire   +3 more sources

Accounting of the Use and Emissions of Polychlorinated Biphenyl Compounds (PCBs) in India, 1951-2100.

Environmental Science and Technology, 2023
Polychlorinated biphenyl compounds (PCBs) are highly toxic organic chemicals still prevalent in the environment. While global inventories of the use and emissions of PCBs have been developed, estimates for individual countries determined using bottom-up ...
J. Parmar, A. Qureshi
semanticscholar   +1 more source

Immunotoxicity of Polychlorinated Biphenyls and Related Compounds

1997
Polychlorinated biphenyls (PCBs), dibenzofurans (PCDFs) and dibenzo-p-dioxins (PCDDs) are hydrocarbons containing two ring structures that can be substituted with a varying number of chlorine atoms, altogether comprising 419 different congeners (Fig. 1).
Vos, JG, de Heer, C, de Swart, RL, Ross, PS, van Loveren, H   +4 more
openaire   +2 more sources

Synthesis, molecular docking, DFT study, and in vitro antimicrobial activity of some 4‐(biphenyl‐4‐yl)‐1,4‐dihydropyridine and 4‐(biphenyl‐4‐yl)pyridine derivatives

Journal of biochemical and molecular toxicology, 2021
The evolution of microbial resistance necessitates the development of new antimicrobial drugs that are more effective than those currently on the market.
A. Malani, Atul H. Makwana, Jahnvi D. Monapara, I. Ahmad, H. Patel, N. Desai   +5 more
semanticscholar   +1 more source

Improving Druggability of Novel Diarylpyrimidine NNRTIs by a Fragment-Based Replacement Strategy: From Biphenyl-DAPYs to Heteroaromatic-Biphenyl-DAPYs.

Journal of Medicinal Chemistry, 2021
A series of novel heteroaromatic-difluoro-biphenyl-diarylpyrimidines were designed as non-nucleoside anti-HIV inhibitors targeting reverse transcriptase by a fragment-based replacement strategy with the purpose of improving the druggability. Hopping five-
Li Ding, C. Pannecouque, E. De Clercq, Chunlin Zhuang, Fener Chen   +4 more
semanticscholar   +1 more source

Polychlorinated biphenyl compounds in milk and dairy products

Zeitschrift f�r Lebensmittel-Untersuchung und -Forschung, 1980
The PCB content of 469 milk and dairy product samples was determined. The fat was extracted and cleaned up through aluminium oxide. The organochlorine pesticides and the PCBs were separated by chromatography through a silica gel column. The PCBs in the purified extracts were perchlorinated to decachlorobiphenyl and determined by gas chromatography. The
Roland Renterghem, Luc Devlaminck
openaire   +1 more source

Reactions of lithium-biphenyl adducts with carbonyl compounds

Bulletin of the Academy of Sciences, USSR Division of Chemical Science, 1966
1. The reactions of lithium-biphenyl adducts in tetrahydrofuran solution with acetaldehyde, benzaldehyde, acetone, cyclohexanone, and ethyl octanoate were carried out. 2. The reaction of lithium-biphenyl adducts with carbonyl compounds takes two courses: condensation of the carbonyl compounds, and organolithium synthesis with formation ...
E. P. Kaplan, Z. I. Kazakova, E. D. Lubuzh, A. D. Petrov   +3 more
openaire   +1 more source

Triplet triplet absorption of biphenyl and related compounds

Chemical Physics Letters, 1974
Abstract Triplet triplet absorption spectra of biphenyl, carbazole and phenanthrene have been studied in rigid glass at 77 K. Oscillator strengths and polarizations are reported. A theoretical study has been performed using the Pariser-Parr-Pople approximation in order to support the band assignments.
D. Lavalette, C. Tetreau
openaire   +1 more source

OPTICAL STABILITY IN BIPHENYL, PHENYLPYRIDYL, AND BIPYRIDYL COMPOUNDS

Canadian Journal of Research, 1950
Comparable ortho-substituted compounds of the biphenyl, 2-phenylpyridyl, and 2,2′-bipyridyl type have been synthesized and resolved, and the resistance to racemization determined. The results are as would have been predicted on geometrical considerations only, the compounds containing nitrogen atoms in the rings not behaving in any abnormal manner.
D. Aziz, J. G. Breckenridge
openaire   +1 more source

Biphenyl tricyclic quinazoline compounds

2012
The invention is directed to certain novel compounds with biphenyl tricyclic quinazoline structure. Specifically, the invention is directed to compounds of formula (I) and salts thereof. The compounds of the invention are multiple inhibitors of tyrosine kinase activity.
CHILIN, ADRIANA, MARZARO, GIOVANNI, GUIOTTO, ADRIANO, CONCONI, MARIA TERESA, CASTAGLIUOLO, IGNAZIO   +4 more
openaire   +1 more source