Results 11 to 20 of about 269,013 (347)

Neglected but not negligible aspects of antidepressants and their availability in bipolar depression

open access: yesBrain and Behavior, 2021
Objectives Although many antidepressants are available, they are not always used appropriately. For appropriate use of antidepressants, the old concept of a linear dose–response relationship, in which the dose is linearly increased to achieve a ...
Takeshi Terao
doaj   +1 more source

Pre- and Post-treatment Levels of Plasma Metabolites in Patients With Bipolar Depression

open access: yesFrontiers in Psychiatry, 2021
Background: Bipolar disorder (BD) is a serious mental disease with complex clinical manifestations and high recurrence rate. The purpose of this study was to detect metabolites related to the diagnosis and efficacy evaluation of bipolar depression in ...
Xiang-Jie Guo   +15 more
doaj   +1 more source

A STUDY COMPARING SOCIO-DEMOGRAPHIC AND CLINICAL PROFILE OF PATIENTS OF UNIPOLAR AND BIPOLAR DEPRESSION.

open access: yesStudent's Journal of Health Research Africa, 2023
Background: Unipolar and bipolar depression are distinguished very distantly, in symptoms, diagnosis, prognosis, course of treatment, neurobiology, and genetics.
Dr. Farheen fatma, Dr .Dhruv
doaj   +1 more source

Neuroinflammation in Bipolar Depression [PDF]

open access: yesFrontiers in Psychiatry, 2020
Bipolar disorder (BD) is a leading cause of worldwide disability among mood disorders. Pathological mechanisms are still vastly unclear, and current treatments with conventional medications are often unsatisfactory in maintaining symptoms control and an adequate quality of life.
Francesco Benedetti   +6 more
openaire   +4 more sources

Music to improve sleep quality in adults with depression-related insomnia (MUSTAFI): study protocol for a randomized controlled trial

open access: yesTrials, 2020
Background Insomnia is a common sleep disorder for adults with depression, with major impact on their quality of life. Previous trials suggest that listening to music may be helpful in the treatment of sleep disturbances in healthy populations, including
Helle Nystrup Lund   +13 more
doaj   +1 more source

Affective temperaments mediate the effect of childhood maltreatment on bipolar depression severity

open access: yesPCN Reports, 2023
Aim Bipolar disorder is a leading disorder contributing to global disease burden, and bipolar depression often becomes severe and refractory. Therefore, clarifying the pathophysiology of bipolar disorder is an urgent issue.
Itsuki Terao   +8 more
doaj   +1 more source

The Role of Ketamine in the Treatment of Bipolar Depression: A Scoping Review

open access: yesBrain Sciences, 2023
Bipolar depression remains a clinical challenge with a quarter of patients failing to respond to initial conventional treatments. Although ketamine has been extensively studied in unipolar depression, its role in bipolar disorder remains inconclusive ...
Muhammad Youshay Jawad   +10 more
doaj   +1 more source

Short-term ketamine use in bipolar depression: a review of the evidence for short-term treatment management

open access: yesFrontiers in Psychiatry, 2023
Bipolar depression constitutes a major problem in psychiatry. It correlates with high suicidality, treatment resistance, chronicity, and poor quality of life. Registered treatment for bipolar depression is limited and insufficient.
Alina Wilkowska, Wiesław Jerzy Cubała
doaj   +1 more source

Trait and state-related characteristics of thalamo-cortical circuit disruption in bipolar disorder: a prospective cross-sectional study

open access: yesFrontiers in Psychiatry, 2023
ObjectiveThe purpose of this study is to investigate the shared and distinct thalamic-cortical circuit between bipolar depression and remission, as well as to investigate the trait and state-related characteristics of the abnormal thalamic-cortical ...
Can Zeng, SuQun Liao, Weidan Pu
doaj   +1 more source

Neurocognition Function of Patients With Bipolar Depression, Unipolar Depression, and Depression With Bipolarity [PDF]

open access: yesFrontiers in Psychiatry, 2021
Much evidence shows that some Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5)-defined unipolar depression (UD) with bipolarity manifests bipolar diathesis. Little is known about the cognitive profiles of patients with depression with bipolarity (DWB).
Zhe Lu   +3 more
openaire   +4 more sources

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