Possible Antidepressant Effects of Memantine—Systematic Review with a Case Study
The treatment of bipolar depression is hampered by the inadequate efficacy of antidepressants, moderate effect of mood stabilizers, and the side effects of some second-generation antipsychotics.
Marek Krzystanek +4 more
doaj +1 more source
Background: Unrecognized bipolar spectrum disorder under cover diagnosis of major depression disorder leads to wrong medications (antidepressants in absence of mood stabilizer), which may switch to mania.
Kinjal Bhupendrasinh Chauhan +4 more
doaj +1 more source
Female genital disorder as adverse symptom of lamotrigine treatment - A serotoninergic effect? [PDF]
The new anticonvulsant, lamotrigine, is becoming an important tool in the treatment of bipolar disorder, including bipolar depression. Its efficacy in bipolar depression might be linked to its inhibition of serotonin uptake.
Amann, Benedikt +2 more
core +1 more source
Subjective and objective indicators of recovery in severe mental illness: a cross-sectional study [PDF]
Background: This study aimed to determine whether subjective dimensions of recovery such as empowerment are associated with self-report of more objective indicators such as level of participation in the community and income from employment.
King, Robert +2 more
core +3 more sources
Lamotrigine in the treatment of schizoaffective disorder [PDF]
There is accumulating evidence for the efficacy of lamotrigine in the treatment of bipolar disorder, including bipolar depression, both as monotherapy and in combination with sodium valproate.
Erfurth, Andreas +2 more
core +1 more source
Cognitive function and lifetime features of depression and bipolar disorder in a large population sample: Cross-sectional study of 143,828 UK Biobank participants [PDF]
Background: This study investigated differences in cognitive performance between middle-aged adults with and without a lifetime history of mood disorder features, adjusting for a range of potential confounders.
Cullen, B. +10 more
core +2 more sources
Comparing the effects of repetitive transcranial magnetic stimulation and electroconvulsive therapy in the treatment of depression : a systematic review and meta-analysis [PDF]
Electroconvulsive therapy (ECT) is the longest standing psychiatric treatment available and has unequivocal benefit in severe depression. However this treatment comes with a number of side effects such as memory impairment.
Micallef-Trigona, Beppe
core +9 more sources
Repetitive transcranial magnetic stimulation (rTMS) is effective in the treatment of depression. However, for the subset of patients with bipolar disorder, less data is available and overall strength of evidence is weaker than for its use in unipolar ...
Abdullah Alhelali +6 more
doaj +1 more source
The study protocol of the Norwegian randomized controlled trial of electroconvulsive therapy in treatment resistant depression in bipolar disorder [PDF]
Background The treatment of depressive phases of bipolar disorder is challenging. The effects of the commonly used antidepressants in bipolar depression are questionable.
Ute Kessler +7 more
core +2 more sources
Depression Preceding Diagnosis of Bipolar Disorder
This paper focuses on depression that precedes an onset of manifest bipolar disorder as early stage bipolar disorder. First, we review how to pragmatically identify the clinical characteristics of patients presenting with an episode of depression who ...
Claire O'Donovan, Martin Alda
doaj +1 more source

