Results 1 to 10 of about 3,359,821 (389)

Staging in bipolar disorder: from theoretical framework to clinical utility

open access: yesWorld Psychiatry, 2017
Illness staging is widely utilized in several medical disciplines to help predict course or prognosis, and optimize treatment. Staging models in psychiatry in general, and bipolar disorder in particular, depend on the premise that psychopathology moves ...
Michael Berk   +2 more
exaly   +2 more sources

Genetics of bipolar disorder

open access: yesThe Application of Clinical Genetics, 2014
Berit Kerner Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, USA Abstract: Bipolar disorder is a common, complex genetic disorder, but the mode of transmission remains to be discovered.
Kerner B
doaj   +6 more sources

Bipolar Disorder [PDF]

open access: yesDepression Research and Treatment, 2012
Bipolar disorder is a serious disorder of mood that is associated with considerable psychosocial and economic morbidity. Even though it is more common than previously thought, it has until relatively recently been somewhat neglected in terms of research when compared to disorders such as schizophrenia and major depression. Recent advances in the fields
COLOMBO , CRISTINA ANNA   +2 more
  +10 more sources

Serum BDNF levels and state anxiety are associated with somatic symptoms in patients with panic disorder

open access: yesFrontiers in Psychiatry, 2023
BackgroundWe aimed to explore the predictive role of serum BDNF and anxiety-related variables in changes in somatic symptoms post-escitalopram treatment in panic disorder (PD) patients.MethodsNinety PD patients and 99 healthy controls (HCs) were enrolled.
Jiaxin Li   +5 more
doaj   +1 more source

Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

open access: yesNature Genetics, 2021
Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-wide association study of 41,917 bipolar disorder cases and 371,549 controls of European ancestry, which identified 64 associated genomic loci.
N. Mullins   +316 more
semanticscholar   +1 more source

Diagnostic Stability of Primary Psychotic Disorders in a Research Sample

open access: yesFrontiers in Psychiatry, 2021
Psychiatric diagnosis is often treated as a stable construct both clinically and in research; however, some evidence suggests that diagnostic change may be common, which may impact research validity and clinical care.
Andrea J. Wood   +7 more
doaj   +1 more source

Bipolar disorder [PDF]

open access: yesEvidence-Based Mental Health, 2003
Bipolar disorder, with mood swings between depression and mania, may affect up to 1.5% of adults, and increases the risk of suicide and disability. Most people improve over time, but two thirds may have residual dysfunction, and at least 40% may have recurrent episodes.We conducted a systematic review and aimed to answer the following clinical ...
Geddes, J, Briess, D
openaire   +9 more sources

Structured physical exercise for bipolar depression: an open-label, proof-of concept study

open access: yesInternational Journal of Bipolar Disorders, 2023
Background Physical exercise (PE) is a recommended lifestyle intervention for different mental disorders and has shown specific positive therapeutic effects in unipolar depressive disorder.
Beny Lafer   +6 more
doaj   +1 more source

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