Results 41 to 50 of about 194,956 (304)

Pilot study of circulating cell-free mitochondrial DNA in relation to brain structure in youth bipolar disorder

open access: yesInternational Journal of Bipolar Disorders
Background Mitochondrial dysfunction is implicated in the neuropathology of bipolar disorder (BD). Higher circulating cell-free mitochondrial DNA (ccf-mtDNA), generally reflecting poorer mitochondrial health, has been associated with greater symptoms ...
Suyi Shao   +8 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

Social cognition and interactive training for first-episode, drug-naïve MDD patients

open access: yesFrontiers in Psychiatry
ObjectiveThis study aimed to explore the impacts of social cognition and interaction training (SCIT) on serum brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF) levels, and psychosocial function in first-episode,
Jiaxin Li   +5 more
doaj   +1 more source

Associations between brain‐derived neurotrophic factor and cognitive impairment in panic disorder

open access: yesBrain and Behavior, 2020
Introduction Our study was designed to examine the relationship between Brain‐Derived Neurotrophic Factor (BDNF) genotypes (rs6265, Val66Met), BDNF plasma levels, and cognitive impairment in Chinese patients with panic disorder (PD).
Wenchen Wang   +5 more
doaj   +1 more source

Cognitive function in bipolar disorder

open access: yesEuropean Psychiatry, 2022
Introduction In bipolar disorder, cognitive deficits persist across mood episodes and euthymia. Despite recent advances, cognitive impairment in bipolar disorder remains poorly understood.
T. Sparding
doaj   +1 more source

Risk taking behaviour in bipolar affective disorder [PDF]

open access: yes, 2010
This piece of research was designed to explore the nature of risk taking behaviour and impulsivity in bipolar affective disorder. Involvement in pleasurable activities that have a high potential, or risk, for unwanted consequences forms one of the DSM IV
Bunch, Kristin
core  

Schizophrenia and Bipolar Disorder in Urban Areas

open access: yes, 2007
Background Earlier studies have shown that schizophrenic patients are more likely to be living in densely populated inner city areas, whereas bipolar patients are more widely distributed.
Cooke, Angela   +5 more
core   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen   +7 more
wiley   +1 more source

El tratamiento a largo plazo del trastorno bipolar

open access: yesPsicodebate, 2015
Las indicaciones medicamentosas para el tratamiento del trastorno bipolar (TB) requieren de una ponderación de la necesidad de tratamiento del episodio en curso y su evolución a largo plazo. Los objetivos principales radicarán en estabilizar el ánimo,
Leonardo Tondo
doaj   +1 more source

Is Bipolar Disorder the Consequence of a Genetic Weakness or Not Having Correctly Used a Potential Adaptive Condition?

open access: yesBrain Sciences, 2022
It is hypothesized that factors associated with bipolar disorder could, uer defined conditions, produce adaptive behaviors. The aim is to verify whether a genetic feature associated with bipolar disorder can be found in people without bipolar disorder ...
Mauro Giovanni Carta   +7 more
doaj   +1 more source

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