Results 41 to 50 of about 1,321,310 (288)

Correlation between Peripheral Levels of Brain-Derived Neurotrophic Factor and Hippocampal Volume in Children and Adolescents with Bipolar Disorder

open access: yesNeural Plasticity, 2015
Pediatric bipolar disorder (PBD) is a serious mental disorder that affects the development and emotional growth of affected patients. The brain derived neurotrophic factor (BDNF) is recognized as one of the possible markers of the framework and its ...
Tatiana Lauxen Peruzzolo   +11 more
doaj   +1 more source

Research progress of the role of gut microbiota in the pathogenesis and treatment of bipolar disorder

open access: yesSichuan jingshen weisheng, 2021
The purpose of this article is to explore the role of gut microbiota in the pathogenesis and treatment of bipolar disorder, so as to provide a new perspective for the clinical diagnosis and treatment of bipolar disorder.
Chu Lingli, Rong Han, Chen Qingchong
doaj   +1 more source

Pediatric Bipolar Disorder [PDF]

open access: yesIndian Journal of Psychological Medicine, 2009
Clinicians are less sensitive in considering the diagnosis of mania in children because of the variations in clinical presentation and because of the high comorbidity with other psychiatric disorders. More often than the elated and expansive mood, irritability and significant aggression may be the presenting symptoms in these cases.
Aravind V, Krishnaram V
openaire   +3 more sources

Differential efficacy of lithium and carbamazepine in the prophylaxis of bipolar disorder: Results of the MAP study [PDF]

open access: yes, 2000
In a randomized clinical trial with an observation period of 2.5 years, the differential efficacy of lithium versus carbamazepine was compared in 171 bipolar patients (DSM-IV).
Waldemar Greil   +3 more
core   +1 more source

Poor self-reported sleep is associated with prolonged white matter T2 relaxation in psychotic disorders

open access: yesFrontiers in Psychiatry
BackgroundPsychotic disorders are characterized by white matter (WM) abnormalities; however, their relationship with the various aspects of illness presentation remains unclear.
Umit Haluk Yesilkaya   +13 more
doaj   +1 more source

Bipolar disorder longitudinal study in Nigeria – Preliminary data on demographic and clinical findings of the study cohort

open access: yesJournal of Affective Disorders Reports, 2023
Background: Bipolar disorder, severe mood disorder characterised by its ability to swing between two contrasting poles of low and elated mood with a return to relatively normal level of functioning, has a lifetime prevalence of up to 2.4%, a heterogenous
Frances Nkechi Adiukwu   +6 more
doaj   +1 more source

Treatment of bipolar disorder [PDF]

open access: yesThe Lancet, 2013
We review recent developments in the acute and long-term treatment of bipolar disorder and identify promising future routes to therapeutic innovation. Overall, advances in drug treatment remain quite modest. Antipsychotic drugs are effective in the acute treatment of mania; their efficacy in the treatment of depression is variable with the clearest ...
John R, Geddes, David J, Miklowitz
openaire   +2 more sources

Pilot study of circulating cell-free mitochondrial DNA in relation to brain structure in youth bipolar disorder

open access: yesInternational Journal of Bipolar Disorders
Background Mitochondrial dysfunction is implicated in the neuropathology of bipolar disorder (BD). Higher circulating cell-free mitochondrial DNA (ccf-mtDNA), generally reflecting poorer mitochondrial health, has been associated with greater symptoms ...
Suyi Shao   +8 more
doaj   +1 more source

Cognitive function in bipolar disorder

open access: yesEuropean Psychiatry, 2022
Introduction In bipolar disorder, cognitive deficits persist across mood episodes and euthymia. Despite recent advances, cognitive impairment in bipolar disorder remains poorly understood.
T. Sparding
doaj   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen   +7 more
wiley   +1 more source

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