Results 51 to 60 of about 195,713 (302)

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

fNIRS-Based characterization of adolescent depression using dynamic functional connectivity biomarkers in a verbal fluency task

BMC Psychiatry
Background The human brain is a dynamic neural system with time-varying functional connectivity (FC) strengths between brain regions. Evidence indicates that adolescents with major depressive disorder (MDD) exhibit decreased average FC strength in ...
Tongxin Li, Yeqing Dong, Qingyan Jiao, Lijun Chu, Jianli Qiu, Yanlei Fu, Yongyan Gao, Zhonghui Ma, Xia Sun, Yong Zhang   +9 more
doaj   +1 more source

Normal Cerebral Oxygen Consumption Despite Elevated Cerebral Blood Flow in Adolescents With Bipolar Disorder: Putative Neuroimaging Evidence of Anomalous Energy Metabolism

Frontiers in Psychiatry, 2019
Background: Regional cerebral blood flow (CBF) is reportedly altered in both adolescents and adults with bipolar disorder (BD). Whether these CBF differences are part of an overall imbalance in cerebral energy homeostasis remains unknown.
Sudhir Karthikeyan, Lisa Fiksenbaum, Anahit Grigorian, Hanzhang Lu, Bradley J. MacIntosh, Bradley J. MacIntosh, Bradley J. MacIntosh, Benjamin I. Goldstein, Benjamin I. Goldstein, Benjamin I. Goldstein, Benjamin I. Goldstein   +10 more
doaj   +1 more source

The feasibility of mindfulness-based cognitive therapy for people with bipolar disorder: a qualitative study

International Journal of Bipolar Disorders, 2020
Background Mindfulness- Based Cognitive Therapy (MBCT) could be a promising psychosocial intervention for people with bipolar disorder (BD). However, little is known about the feasibility of MBCT for people with BD.
Imke Hanssen, Nicole van der Horst, Marieke Boele, Marc Lochmann van Bennekom, Eline Regeer, Anne Speckens   +5 more
doaj   +1 more source

Regional lithium prescription rates and recurrence in bipolar disorder

International Journal of Bipolar Disorders, 2021
Background Lithium is the best documented maintenance treatment in bipolar disorder, but its use varies considerably across and within countries. It is not known whether regional differences in lithium prescription rates translate to differing regional ...
Martin Sköld, Sindre Rolstad, Erik Joas, Mathias Kardell, Erik Pålsson, Guy M. Goodwin, Mikael Landén   +6 more
doaj   +1 more source

What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group [PDF]

, 2022
MRI-derived brain measures offer a link between genes, the environment and behavior and have been widely studied in bipolar disorder (BD). However, many neuroimaging studies of BD have been underpowered, leading to varied results and uncertainty ...
ENIGMA Bipolar Disorder Working Group
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White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Behavioural biomarkers and mobile mental health: a new paradigm

International Journal of Bipolar Disorders, 2018
Over recent decades, the field of psychiatry has allocated a vast amount of resources and efforts to make available more accurate and objective methods to diagnose, assess and monitor treatment outcomes in psychiatric disorders.
Diego Hidalgo-Mazzei, Allan H. Young, Eduard Vieta, Francesc Colom   +3 more
doaj   +1 more source

Psychiatric hospital utilisation following lithium discontinuation in patients with bipolar I or II disorder: A mirror-image study based on the lisie retrospective cohort

European Psychiatry, 2021
Introduction Evidence for lithium as a maintenance treatment for bipolar disorder type II remains limited since most treatment-prevention studies focus on bipolar disorder type I or do not distinguish between types of bipolar disorder.
L. Öhlund, M. Ott, M. Bergqvist, S. Oja, R. Lundqvist, M. Sandlund, E. Salander Renberg, U. Werneke   +7 more
doaj   +1 more source

Wāhine Whaiora: Māori Women's Experiences of Bipolar Disorder and their Pathways to Recovery [PDF]

, 2014
This research examines the unique, lived experiences of wāhine Māori (Māori women) who have been diagnosed with bipolar affective disorder and who are currently living ‘well’.
Harris, Parewahaika Erenora Te Korowhiti
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