Violent suicidal behaviour in bipolar disorder is associated with nitric oxide synthase 3 gene polymorphism [PDF]
, 2015 J. Oliveira +15 more
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Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension
Advanced Science, EarlyView.H4R and its downstream TRPV1 channel mediate the excitatory effect of TMN histaminergic afferent inputs on GABAergic sympathoinhibitory neurons in RVMM. Intranasal delivery of selective H4R agonist VUF 8430 suppresses renal sympathetic outflow and elicits sustained depressor and bradycardia responses in SHRs and CUMS‐induced hypertensive rats ...
Ying Shi +18 more
wiley +1 more source
Advanced Science, EarlyView.This study examines major depressive disorder with atypical features and psychotic symptoms through a multi‐omics precision medicine approach. By integrating clinical assessments, WBC scRNA‐seq, plasma proteomics, and brain organoid models, it uncovers immune dysregulation, synaptic protein alterations, and stress‐sensitive neuronal changes.
Insook Ahn +5 more
wiley +1 more source
The effect of dialectical behavior therapy on executive function in patients with a bipolar disorder [PDF]
, 2018 Background: Bipolar disorder is a debilitating psychiatric disorder characterized by recurrent depression, manic and hippomanic episodes. The effect of a dialectical behavior therapy on executive functions in bipolar disorders has not been addressed so ...
Afshari, Behrooz +2 more
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A clinical study comparing manic and mixed episodes in patients with bipolar disorder [PDF]
, 2007 Ângela Maria Schwartzmann +9 more
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Cortical haemodynamic response during the verbal fluency task in patients with bipolar disorder and borderline personality disorder: a preliminary functional near-infrared spectroscopy study [PDF]
, 2021 Syeda Fabeha Husain +5 more
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Advanced Science, EarlyView.Schizophrenia (SCZ) is linked to synaptic structural deficits driven by dysregulated noncoding RNAs. Using the novel ceRNAxis pipeline, THUMPD3‐AS1/miR‐485‐5p/ARHGAP8 is identified as a key regulator of actin cytoskeletal remodeling through noncanonical RhoB/C‐ROCK2 signaling. Modulating this axis ameliorates SCZ‐like phenotypes in mice and aligns with
Xiaojuan Gong +9 more
wiley +1 more source
Advanced Science, EarlyView.Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao +4 more
wiley +1 more source
Bridges Between Bipolar and Borderline Personality Disorders: Clarifying Comorbidity Through the Analysis of the Complex Network of Connections Between Symptoms [PDF]
, 2018 Daniel Castro +3 more
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