Results 201 to 210 of about 194,956 (304)

Virtual Twin Approach Using Physiologically Based Pharmacokinetic Modeling to Support Precision Dosing of Valproic Acid in Geriatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Personalized dosing is particularly important for drugs with narrow therapeutic indices in geriatric patients, who exhibit substantial physiological variability and limited pharmacokinetic (PK) evidence to guide individualized dose selection. Valproic acid (VPA) is an effective treatment option for bipolar disorder in older adults, yet dosing largely ...
Yoo Jin Jang, Dong‐Gyu Heo, Eunjin Hong   +2 more
wiley   +1 more source

Texture-Based MRI Analysis Reveals Microstructural Alterations in the Putamen in Bipolar Disorder. [PDF]

Medicina (Kaunas)
Gül Ö, Baykara S, Namlı MN, Baykara M.   +3 more
europepmc   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

Neuroinflammation and white matter microstructure as mediators of cognitive deficits in offspring of parents with bipolar disorder. [PDF]

Brain Commun
Li X, Zou W, Shao R, Lu W, Chao L, Zhao X, Su KP, Lin K.   +7 more
europepmc   +1 more source

Psychiatric Morbidity Is Overrepresented in Young Girls at High Risk of Developing Anorexia Nervosa

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Psychiatric comorbidity frequently presents in anorexia nervosa (AN). Yet, the premorbid mental health status is relatively unknown. The aim of this study was to map out psychiatric morbidity and psychopathology among girls at familial high risk (FHR) of developing AN, thereby detecting possible underlying vulnerabilities preceding ...
Karin Dahlin, Kajsa Järvholm, Jovanna Dahlgren, Elisabet Wentz   +3 more
wiley   +1 more source

The Regulatory Potential of Long Non-Coding RNAs in Bipolar Disorder. [PDF]

Int J Mol Sci
Li S, Fu Y, Wang Z, Zhang Y, Sun T, Miao N.   +5 more
europepmc   +1 more source

When Is Improvement Possible? A Necessity‐Based Analysis of Short‐Term Eating Disorder Symptom Improvement During Inpatient Treatment

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Eating‐disorder–specific functional impairment may represent a boundary condition for treatment response, yet this possibility has rarely been examined. We investigated whether baseline functional impairment constrains short‐term eating‐disorder symptom improvement, indexed by change in EDE‐Q Global scores during inpatient treatment ...
Paolo Meneguzzo, Patrizia Todisco
wiley   +1 more source

Correction to "Living With Bipolar Disorder and Medication PRN-A Case-Report". [PDF]

Bipolar Disord
europepmc   +1 more source

Functional impairment in patients with remitted bipolar disorder [PDF]

, 2007
Martínez-Aran, Anabel, Kapczinski, Flávio Pereira, Vieta, Eduard, Sanchez-Moreno, Jose, Salamero, Manel, Rosa, Adriane Ribeiro, Franco, C., Reinares, Maria   +7 more
core  

Reward Processing in Binge Eating and Harmful Drinking: A Systematic Review

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Binge eating and harmful drinking commonly co‐occur, which worsens the physical and psychological consequences associated with either behavior alone. Reward processing alterations have been demonstrated among individuals who engage in binge eating or harmful drinking alone; however, there is limited understanding of how different ...
Taylor N. Breddy, Kendall M. Schmidt, Lindsay P. Bodell   +2 more
wiley   +1 more source