Results 41 to 50 of about 387,451 (287)

Pilot study of circulating cell-free mitochondrial DNA in relation to brain structure in youth bipolar disorder

open access: yesInternational Journal of Bipolar Disorders
Background Mitochondrial dysfunction is implicated in the neuropathology of bipolar disorder (BD). Higher circulating cell-free mitochondrial DNA (ccf-mtDNA), generally reflecting poorer mitochondrial health, has been associated with greater symptoms ...
Suyi Shao   +8 more
doaj   +1 more source

Social cognition and interactive training for first-episode, drug-naïve MDD patients

open access: yesFrontiers in Psychiatry
ObjectiveThis study aimed to explore the impacts of social cognition and interaction training (SCIT) on serum brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF) levels, and psychosocial function in first-episode,
Jiaxin Li   +5 more
doaj   +1 more source

Normal Cerebral Oxygen Consumption Despite Elevated Cerebral Blood Flow in Adolescents With Bipolar Disorder: Putative Neuroimaging Evidence of Anomalous Energy Metabolism

open access: yesFrontiers in Psychiatry, 2019
Background: Regional cerebral blood flow (CBF) is reportedly altered in both adolescents and adults with bipolar disorder (BD). Whether these CBF differences are part of an overall imbalance in cerebral energy homeostasis remains unknown.
Sudhir Karthikeyan   +10 more
doaj   +1 more source

The feasibility of mindfulness-based cognitive therapy for people with bipolar disorder: a qualitative study

open access: yesInternational Journal of Bipolar Disorders, 2020
Background Mindfulness- Based Cognitive Therapy (MBCT) could be a promising psychosocial intervention for people with bipolar disorder (BD). However, little is known about the feasibility of MBCT for people with BD.
Imke Hanssen   +5 more
doaj   +1 more source

Regional lithium prescription rates and recurrence in bipolar disorder

open access: yesInternational Journal of Bipolar Disorders, 2021
Background Lithium is the best documented maintenance treatment in bipolar disorder, but its use varies considerably across and within countries. It is not known whether regional differences in lithium prescription rates translate to differing regional ...
Martin Sköld   +6 more
doaj   +1 more source

Subjective and objective indicators of recovery in severe mental illness: a cross-sectional study [PDF]

open access: yes, 2010
Background: This study aimed to determine whether subjective dimensions of recovery such as empowerment are associated with self-report of more objective indicators such as level of participation in the community and income from employment.
King, Robert   +2 more
core   +3 more sources

Nerve Excitability in Asymptomatic Carriers and Amyotrophic Lateral Sclerosis Patients With C9orf72

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We investigated the effects of C9orf72 mutation carriership on peripheral nerve excitability in asymptomatic individuals from families with a history of C9orf72 amyotrophic lateral sclerosis (ALS) and patients. Methods We included 47 asymptomatic individuals from families with a history of C9orf72 ALS, of whom 23 were carriers (C9 ...
Diederik J. L. Stikvoort García   +3 more
wiley   +1 more source

Behavioural biomarkers and mobile mental health: a new paradigm

open access: yesInternational Journal of Bipolar Disorders, 2018
Over recent decades, the field of psychiatry has allocated a vast amount of resources and efforts to make available more accurate and objective methods to diagnose, assess and monitor treatment outcomes in psychiatric disorders.
Diego Hidalgo-Mazzei   +3 more
doaj   +1 more source

Psychiatric hospital utilisation following lithium discontinuation in patients with bipolar I or II disorder: A mirror-image study based on the lisie retrospective cohort

open access: yesEuropean Psychiatry, 2021
Introduction Evidence for lithium as a maintenance treatment for bipolar disorder type II remains limited since most treatment-prevention studies focus on bipolar disorder type I or do not distinguish between types of bipolar disorder.
L. Öhlund   +7 more
doaj   +1 more source

Bipolar disorder and age-related functional impairment [PDF]

open access: yes, 2009
OBJECTIVE: Although bipolar disorder is a major contributor to functional impairment worldwide, an independent impact of bipolar disorder and ageing on functioning has yet to be demonstrated.
Adriane Ribeiro Rosa   +23 more
core   +3 more sources

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