Results 51 to 60 of about 3,489,237 (370)

Bipolar disorder longitudinal study in Nigeria – Preliminary data on demographic and clinical findings of the study cohort

Journal of Affective Disorders Reports, 2023
Background: Bipolar disorder, severe mood disorder characterised by its ability to swing between two contrasting poles of low and elated mood with a return to relatively normal level of functioning, has a lifetime prevalence of up to 2.4%, a heterogenous
Frances Nkechi Adiukwu, Olufisayo Adesokun, Izuchukwu Metu, Isoboye Jack, Collins Ekwubiri, joy Iyanuoluwapo Igbari, Chidozie Chukwujekwu   +6 more
doaj   +1 more source

Impact of a cis-associated gene expression SNP on chromosome 20q11.22 on bipolar disorder susceptibility, hippocampal structure and cognitive performance. [PDF]

, 2016
BackgroundBipolar disorder is a highly heritable polygenic disorder. Recent enrichment analyses suggest that there may be true risk variants for bipolar disorder in the expression quantitative trait loci (eQTL) in the brain.AimsWe sought to assess the ...
Bellivier, F., Bergen, S. E., Castelao, E., Chen, C., Chen, C., Cichon, S., Degenhardt, F. A., Dong, Q., Etain, B., Fuller, C. K., Fullerton, J. M., Gordon, S. D., Grigoroiu-Serbanescu, M., Henry, C., Hultman, C. M., Hyde, T. M., Jamain, S., Kahn, J. P., Kleinman, J. E., Kutalik, Z., Landen, M., Leboyer, M., Li, H., Li, M., Li, X., Liu, C., Liu, J., Luo, X. J., Martin, N. G., Mattheisen, M., Medland, S. E., Mitchell, P. B., Montgomery, G. W., Moo, D. S. Consortium, Muhleisen, T. W., Nothen, M. M., Preisig, M., Rietschel, M., Schofield, P. R., Schulze, T. G., Su, B., Swedish Bipolar Study, Group, Weinberger, D. R., Wright, A., Yao, Y. G., Zhang, C., Zhang, W.   +46 more
core   +1 more source

Mapping the Heterogeneous Phenotype of Schizophrenia and Bipolar Disorder Using Normative Models

JAMA psychiatry, 2018
Importance Schizophrenia and bipolar disorder are severe and complex brain disorders characterized by substantial clinical and biological heterogeneity.
T. Wolfers, N. T. Doan, T. Kaufmann, D. Alnæs, T. Moberget, I. Agartz, J. Buitelaar, T. Ueland, I. Melle, B. Franke, O. Andreassen, C. Beckmann, L. Westlye, A. Marquand   +13 more
semanticscholar   +1 more source

Poor self-reported sleep is associated with prolonged white matter T2 relaxation in psychotic disorders

Frontiers in Psychiatry
BackgroundPsychotic disorders are characterized by white matter (WM) abnormalities; however, their relationship with the various aspects of illness presentation remains unclear.
Umit Haluk Yesilkaya, Umit Haluk Yesilkaya, Xi Chen, Xi Chen, Lauren Watford, Emma McCoy, Meltem Sen, Ilgin Genc, Fei Du, Fei Du, Dost Ongur, Dost Ongur, Cagri Yuksel, Cagri Yuksel   +13 more
doaj   +1 more source

Examining cognition across the bipolar / schizophrenia diagnostic spectrum [PDF]

, 2018
BACKGROUND: Cognitive impairments are well-established features of schizophrenia, but there is ongoing debate about the nature and degree of cognitive impairment in patients with schizoaffective disorder and bipolar disorder.
Hamshere, Marian L., Hubbard, Leon, Jones, Ian, Legge, Sophie, Lynham, Amy, Owen, Michael, Tansey, Katherine, Walters, James   +7 more
core   +1 more source

Associations between brain‐derived neurotrophic factor and cognitive impairment in panic disorder

Brain and Behavior, 2020
Introduction Our study was designed to examine the relationship between Brain‐Derived Neurotrophic Factor (BDNF) genotypes (rs6265, Val66Met), BDNF plasma levels, and cognitive impairment in Chinese patients with panic disorder (PD).
Wenchen Wang, Yuanyuan Liu, Shuqing Luo, Xiaoyun Guo, Xingguang Luo, Yong Zhang   +5 more
doaj   +1 more source

Cognitive function in bipolar disorder

European Psychiatry, 2022
Introduction In bipolar disorder, cognitive deficits persist across mood episodes and euthymia. Despite recent advances, cognitive impairment in bipolar disorder remains poorly understood.
T. Sparding
doaj   +1 more source

Pilot study of circulating cell-free mitochondrial DNA in relation to brain structure in youth bipolar disorder

International Journal of Bipolar Disorders
Background Mitochondrial dysfunction is implicated in the neuropathology of bipolar disorder (BD). Higher circulating cell-free mitochondrial DNA (ccf-mtDNA), generally reflecting poorer mitochondrial health, has been associated with greater symptoms ...
Suyi Shao, Yi Zou, Kody G. Kennedy, Mikaela K. Dimick, Ana C. Andreazza, L. Trevor Young, Vanessa F. Goncalves, Bradley J. MacIntosh, Benjamin I. Goldstein   +8 more
doaj   +1 more source

Social cognition and interactive training for first-episode, drug-naïve MDD patients

Frontiers in Psychiatry
ObjectiveThis study aimed to explore the impacts of social cognition and interaction training (SCIT) on serum brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF) levels, and psychosocial function in first-episode,
Jiaxin Li, Ru Li, Dazhi Li, Shiyi Suzy Ji, Xingguang Luo, Yong Zhang   +5 more
doaj   +1 more source

El tratamiento a largo plazo del trastorno bipolar

Psicodebate, 2015
Las indicaciones medicamentosas para el tratamiento del trastorno bipolar (TB) requieren de una ponderación de la necesidad de tratamiento del episodio en curso y su evolución a largo plazo. Los objetivos principales radicarán en estabilizar el ánimo,
Leonardo Tondo
doaj   +1 more source