Results 81 to 90 of about 1,321,310 (288)

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou   +6 more
wiley   +1 more source

Wāhine Whaiora: Māori Women's Experiences of Bipolar Disorder and their Pathways to Recovery [PDF]

open access: yes, 2014
This research examines the unique, lived experiences of wāhine Māori (Māori women) who have been diagnosed with bipolar affective disorder and who are currently living ‘well’.
Harris, Parewahaika Erenora Te Korowhiti
core  

Predominant polarity as a potential moderator of group CBT outcomes in bipolar disorder: an exploratory post-hoc analysis

open access: yesFrontiers in Psychiatry
IntroductionBipolar disorder (BD) is a chronic and severe mood disorder, characterized by recurrent episodes of mania, hypomania, and depression. Adjacent to pharmacotherapy, positive evidence has been found for the benefit of adding cognitive behavioral
Tatiana Cohab   +3 more
doaj   +1 more source

Los trastornos bipolares hoy: más allá del DSM–5

open access: yesPsicodebate, 2015
Los trastornos bipolares constituyen un complejo grupo de enfermedades mentales recurrentes que presentan una alta prevalencia en la población general. Las clasificaciones actuales, como el ICD–10 y el DSM–5, constituyen un avance significativo para su ...
Gustavo H. Vázquez
doaj   +1 more source

Bipolar Disorders

open access: yes, 2014
Bipolar disorder is characterized by (hypo)manic episodes and depressive episodes which alternate with euthymic periods. It causes serious disability with poor outcome, increased suicidality risk, and significant societal costs. This chapter describes the findings of the PET/SPECT research efforts and the current ideas on the pathophysiology of bipolar
Haarman, Bartholomeus C. M.   +5 more
openaire   +2 more sources

Epidemiology of Bipolar Disorders [PDF]

open access: yesEpilepsia, 2005
Summary:  Bipolar, or manic–depressive, disorders are frequent and severe mental illnesses associated with considerable morbidity and mortality. Epilepsy and bipolar disorder could probably share some aspects of pathophysiology because manic as well as depressive symptoms are seen in patients with seizures, and a number of antiepileptic drugs are ...
Michael, Bauer, Andrea, Pfennig
openaire   +2 more sources

Covalent Functionalization of 2D Semiconductors: A Roadmap to Advanced Electronic Devices

open access: yesAdvanced Functional Materials, EarlyView.
This Review presents recent advances in the covalent functionalization strategies for two‐dimensional semiconductors and their implementation in modern technologies. Layered materials are modified through diverse molecular chemistries (e.g., thiols, diazonium salts, alkyl halides, and electron‐deficient species) to tailor their surface properties ...
Ramiro Quirós‐Ovies   +2 more
wiley   +1 more source

Characterizing heterogeneity in motivational impairments in psychosis

open access: yesFrontiers in Psychiatry
IntroductionMotivational impairments are a hallmark symptom of psychotic disorders. However, motivation is a multidimensional construct believed to be underpinned by different neural mechanisms and differentially impaired both between and within ...
Kathryn E. Lewandowski   +5 more
doaj   +1 more source

Charge‐Polarized Ni─S4 Single‐Atom Sites Drive Selective Photoreforming of Poly(lactic acid) to Lactate and Hydrogen

open access: yesAdvanced Functional Materials, EarlyView.
Atomically dispersed Ni–S4 sites on CdS nanorods induce interfacial charge polarization, directing photogenerated electrons to H2 evolution and holes to selective ester‐bond cleavage of poly(lactic acid). Without sacrificial reagents, this charge‐coupled system produces lactate while suppressing overoxidation, achieving an H2 evolution rate of 41.74 ...
Yu Yao   +8 more
wiley   +1 more source

The Stanley Foundation Bipolar Network: Results of the naturalistic follow-up study after 2.5 years of follow-up in the German centres [PDF]

open access: yes, 2002
The Stanley Foundation Bipolar Network (SFBN) is an international, multisite network investigating the characteristics and course of bipolar disorder.
Hummel, B.   +9 more
core   +1 more source

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