Results 181 to 190 of about 74,871 (293)

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

open access: yesiNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu   +22 more
wiley   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

open access: yesInterdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi   +13 more
wiley   +1 more source

Electrically Evoked Compound Action Potentials in Spinal Cord Stimulation: Implications for Preclinical Research Models

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives The study aimed to assess the feasibility of recording electrically evoked compound action potentials (ECAPs) from the rat spinal cord. To achieve this, we characterized electrophysiological responses of dorsal column (DC) axons from electrical stimulation and quantified the relationship between ECAP and motor thresholds (ECAPTs and
Birte Elisabeth Dietz   +3 more
wiley   +1 more source

Reversing brain aging: Targeting energy metabolism in endogenous neural stem cells

open access: yesInterdisciplinary Medicine, EarlyView.
Mechanism of endogenous neural stem cells (eNSCs) energy metabolism disorder leading to brain aging and targeted eNSCs intervention strategies (By biorender). The disorder of energy metabolism of eNSCs can lead to their resting and aging, and eventually lead to brain aging.
Chong Chen   +6 more
wiley   +1 more source

Cold Gas Sprayed Titanium Coating for Corrosion Protection of Bipolar Plates in Proton Exchange Membrane Water Electrolysis

open access: yesMaterials and Corrosion, EarlyView.
Climate‐neutral green hydrogen is produced via water electrolysis using renewable energy. This study explores using cold gas spraying to apply titanium coatings on steel bipolar plates for proton exchange membrane water electrolyzers. The coating shows effective corrosion protection, presenting a promising solution for future designs.
Kirsten Bobzin   +3 more
wiley   +1 more source

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