Results 201 to 210 of about 1,301,449 (290)

Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino   +3 more
wiley   +1 more source

Relevance of allostasis and allostatic load in bipolar disorder [PDF]

open access: yes, 2007
Kapczinski, Flávio Pereira   +3 more
core   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli   +5 more
wiley   +1 more source

Application of Magnesium Metal as Anode in Batteries

open access: yesMetalMat, EarlyView.
When used as an anode, magnesium metal offers several advantages, including a high volumetric capacity, environmental friendliness, abundant natural reserves, and a low tendency for dendrite growth. Battery types employing magnesium as the anode include rechargeable magnesium‐ion batteries, aqueous magnesium‐ion batteries, magnesium–air batteries, and ...
Yuanjie Zhang   +5 more
wiley   +1 more source

Congenital Intraoral Synechiae: A Scoping Review of Airway, Feeding, and Surgical Management

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To map the existing literature on congenital intraoral synechiae and summarize reported anatomic patterns, clinical presentation, associated anomalies/syndromes, and outcomes to inform standardized diagnostic and therapeutic approaches. Data Sources PubMed, CINAHL, Embase, Web of Science, and Google Scholar were searched from January
Jason Bernier, Mathieu Bergeron
wiley   +1 more source

Validation of Electrostrictive Performance of P(VDF‐TrFE‐CFE) for kHz Range Applications

open access: yesJournal of Polymer Science, EarlyView.
This study demonstrates that the high‐frequency deformation of the relaxor ferroelectric polymer P(VDF–TrFE–CFE) is governed by Maxwell's electrostriction, confirming its suitability for fast electromechanical applications. Combining original high‐frequency mechanical characterization, laser vibrometry measurements, and numerical modeling, a ...
Audrey Michel   +3 more
wiley   +1 more source

MXene‐Based Flexible Memory and Neuromorphic Devices

open access: yesSmall, EarlyView.
The unique two‐dimensional structure, excellent electrical conductivity, and diverse surface groups of MXenes have garnered significant attention. Coupled with their exceptional flexibility, MXene‐based devices hold immense potential for flexible memory and neuromorphic systems. This review comprehensively discusses the fundamentals of flexible devices,
Yan Li   +13 more
wiley   +1 more source

Memristors Based on Ferroelectric Cu‐Deficient Copper Indium Thiophosphate for Multilevel Storage and Neuromorphic Computing

open access: yesSmall, EarlyView.
Different from CIPS with threshold switching behaviors, Cu‐deficient CIPS* shows stable non‐volatile digital and analog RS. Owing to the formation of metallic IPS at the LRS, CIPS* memristors demonstrate high ON/OFF ratio and endurance stability, which can be utilized to implement multilevel storage.
Mengdie Li   +6 more
wiley   +1 more source

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