Results 211 to 220 of about 74,871 (293)

In Vitro Reconstruction of Axonal Heat Sensing with a Photothermal Nerve‐on‐a‐Chip

open access: yesSmall, EarlyView.
A photothermal nerve‐on‐a‐chip platform is presented that enables precise, localized heating of sensory axons with simultaneous electrical recording. The system reveals millisecond‐scale dynamics of heat‐evoked neural activity and provides a new approach to study how temperature‐dependent ion channel behavior is translated into axonal firing.
Koji Sakai   +6 more
wiley   +1 more source

Deciphering Interfacial Electronic Interactions Between Iridium Oxide and Ni‐Based Supports for High‐Current‐Density Anion Exchange Membrane Water Electrolysis

open access: yesSmall, EarlyView.
This study develops binder‐free IrO2–Ni‐based electrodes through liquid‐phase synthesis to elucidate how Ni‐based support chemistry governs interfacial electronic interactions and oxygen evolution reaction (OER) performance. The IrO2–Ni2P electrode exhibits superior activity and durability, attributed to strong interfacial charge transfer that ...
Yeongbin Lee   +11 more
wiley   +1 more source

Biomaterial‐Integrated Electroporation for Therapeutic Delivery: From Gene Editing to Tumor Ablation and Immune Modulation

open access: yesSmall, EarlyView.
Biomaterial‐integrated electroporation establishes a programmable therapeutic interface that coordinates electric‐field modulation, transient or irreversible membrane permeabilization, cargo stabilization, and immune remodeling. This Review highlights how nanocarriers, hydrogels, and bioelectronic interfaces expand electroporation from conventional ...
Binbin Ji   +13 more
wiley   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

open access: yesVIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe   +8 more
wiley   +1 more source

Novel Surgical Strategy System for Juvenile Nasopharyngeal Angiofibroma: A Focus on Feeding Artery Management

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives For intraoperative bleeding control in patients with juvenile nasopharyngeal angiofibroma (JNA), we developed a novel surgical strategy system. This system is focused on feeding artery management, based on the spatial relationship between the tumor entity and feeding artery as determined by three‐dimensional reconstruction.
Nian‐Zhen Zheng   +10 more
wiley   +1 more source

Epiglottis Collapse in Individuals With Obstructive Sleep Apnea

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Obstructive sleep apnea (OSA) is a common sleep disorder characterized by repeated upper airway collapse during sleep. The epiglottis, often overlooked in conventional assessments, has emerged as a site of significant obstruction in OSA.
Dan Chen   +11 more
wiley   +1 more source

Mapping the lineage of prostate tissue ablation medical device predicates for focal therapy of prostate cancer approved via the FDA 510(k) clearance pathway

open access: yesSurgical Practice, EarlyView.
Abstract Objective Medical devices are reviewed by the US Food and Drug Administration (FDA) for safety and effectiveness. Class II devices can receive 510(k) clearance if they are “substantially equivalent” to an existing predicate device. This process can be repeated iteratively, leading to a lineage of predicates for newly cleared devices.
Yiting Lin   +3 more
wiley   +1 more source

Slit2/Robo Signaling Restores Diabetic Erectile Function via Neurovascular Remodeling

open access: yesAndrology, EarlyView.
ABSTRACT Background Diabetes mellitus‐induced erectile dysfunction (DMED) is a common and debilitating vascular‐neurogenic complication of diabetes. The poor responsiveness of DMED patients to phosphodiesterase type‐5 inhibitors underscores the need for therapies capable of restoring both endothelial integrity and cavernous nerve function.
Sen Fu   +7 more
wiley   +1 more source

Umbilical Cord Blood–Derived Extracellular Vesicles Enhance Neurovascular Regeneration and Improve Erectile Function in a Mouse Model of Bilateral Cavernous Nerve Injury

open access: yesAndrology, EarlyView.
ABSTRACT Background Erectile dysfunction (ED) secondary to cavernous nerve injury (CNI), such as that occurring after radical prostatectomy, remains a significant clinical challenge, particularly among patients who do not respond to phosphodiesterase Type 5 inhibitors (PDE5i).
Minh Nhat Vo   +6 more
wiley   +1 more source

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