Results 101 to 110 of about 5,093,229 (397)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

« Si on peut vous éviter une balafre […], vous accouchez comme une fleur ! » : réguler l’usage de la césarienne à l’hôpital public dans la France contemporaine

open access: yesAnthropologie & Santé
The rate of Cesarean sections in France has remained stable over the last twenty years, after a continuous increase until the 1990s. Based on observations made in a public hospital and interviews with health professionals and patients who have given ...
Maëlys Bar
doaj   +1 more source

Pathways of the determinants of unfavourable birth outcomes in Kenya

open access: yes, 2003
This paper explores the pathways of the determinants of unfavourable birth outcomes, such as premature birth, the size of the baby at birth, and Caesarean section deliveries in Kenya, using graphical loglinear chain models. The results show that a number
Diamond, Ian   +3 more
core  

How do pregnancy and birth experiences influence planned place of birth in future pregnancies? Findings from a longitudinal, narrative study. [PDF]

open access: yes, 2015
A perception that first birth is more risky than subsequent births has led to women planning births in Obstetric Units, and care providers supporting these choices.
Fulop, NJ
core  

Julian’s Birth [PDF]

open access: yesThe Journal of Perinatal Education, 2014
A grandmother of seven and childbirth educator shares her daughter’s successful vaginal birth after cesarean (VBAC) birth story in Switzerland.
openaire   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Birth size and breast cancer risk: Re-analysis of individual participant data from 32 studied [PDF]

open access: yes, 2008
Background Birth size, perhaps a proxy for prenatal environment, might be a correlate of subsequent breast cancer risk, but findings from epidemiological studies have been inconsistent.
Collaborative, GOP-NRFASROBC   +3 more
core  

Association of Mothers' Perception of Neighborhood Quality and Maternal Resilience with Risk of Preterm Birth. [PDF]

open access: yes, 2015
We examined the associations of mothers' perception of neighborhood quality and maternal resilience with risk of preterm birth and whether maternal resilience moderated the effect of neighborhood quality perception.
Bhatia, Namrata   +4 more
core   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Pregnancy outcomes among daycare employees in Finland

open access: yesScandinavian Journal of Work, Environment & Health, 2010
OBJECTIVE: The aim of this study was to investigate whether working as a daycare employee increases the risk of perinatal death, pre-term birth, low birth weight, smallness for gestational age, or congenital malformations.
Anita Riipinen   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy