Life, Birth and Death in Democritus. Atomistic Reflections Between Physics and Ethics
The subject of life, birth and death constitutes one of the main topics in Democritus’ reflection on human questions. He seeks to understand what men think about the processes of birth and death and how they, accordingly, determine their behavior and ...
Miriam Campolina Diniz Peixoto
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Estimating plasma volume in neonatal Holstein calves fed one or two feedings of a lacteal-based colostrum replacer using Evans blue dye and hematocrit values at various time points. [PDF]
Twenty-eight Holstein calves were blocked by birth date and randomly assigned to one of two treatments to investigate the effect of colostrum replacer (CR) feeding regimen on plasma volume (PV).
Cabral, Rosemarie G., Ph.D. +3 more
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Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
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Gebelerin Gebelikte İyi Olma Hali ve Gebelik Deneyimlerinin Doğum İnançlarıyla İlişkisi
Giriş: Prenatal dönemde, olumlu deneyimler, gebelikte iyi olma hali, sağlıklı bir doğum süreci için önemlidir. Amaç: Araştırmada gebelerin gebelikte iyi olma hali ve gebelik deneyimlerinin doğum inançlarıyla ilişkisini incelemek amaçlandı.
Zehra Çerçer, Duygu Ayar
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Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
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Spatial Epidemiologic Analysis of Fetal Birth Defects in Guangxi, China
Zhenren Peng,1– 5,* Xiuning Huang,4,5,* Jie Wei,4,5,* Biyan Chen,4,5 Lifang Liang,4,5 Baoying Feng,4,5 Qiufen Wei,1– 5 Sheng He1– 5 1Birth Defects Research Laboratory, Guangxi Clinical Research Center for Birth Defects, Nanning ...
Peng Z +7 more
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Inviting Newton to Visit the Delivery Room the Role of Gravity During Childbirth
Michael Stark,1 Ospan Mynbaev,1 Antonio Malvasi,1,2 Andrea Tinelli1,3 1The New European Surgical Academy, Berlin, Germany; 2Department of Obstetrics and Gynecology, Santa Maria Hospital G.V.M.
Stark M, Mynbaev O, Malvasi A, Tinelli A
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HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
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Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
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Faith in Numbers—Re-quantifying the English Quaker Population during the Long Eighteenth Century
The Religious Society of Friends was traditionally disinclined to define “membership„ in pursuit of the Quaker mission to create a worldwide church.
Andrew Fincham
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