Results 51 to 60 of about 3,944,762 (261)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Gaye Çarmıklı Koleksiyonu ve Sadberk Hanım Müzesi’nden Doğuran Kadın Amuletleri / The Amulets for Woman Giving Birth in the Gaye Çarmıklı Collection and Sadberk Hanım Museum

Arkhaia Anatolika, 2023
The amulets of mold-made glass depicted a nude squatting fat female figure, with both hands placed in her genital area are a group of finds that are concentrated in ancient cities on the Egyptian, Levant and North African coasts during the Hellenistic ...
Çilem UYGUN, Melih Arslan
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Calls to a home birth helpline: empowerment in childbirth [PDF]

, 2005
In the UK a woman has the right to decide to give birth at home, irrespective of whether she is expecting her first or a subsequent child and of any perceived ‘risk’ factors.
Arms, Bergstrom, Calandra, Campbell, Campbell, Celia Kitzinger, Chamberlain, Coslett, Davies, Davis-Floyd, Davis-Floyd, Davis-Floyd, Dodds, Dowswell, Emslie, Floyd, Fordham, Garcia, Gready, Henderson, Hodnett, Hosein, Hundley, Katz-Rothman, Kitzinger, Kitzinger, Kitzinger, Kitzinger, Klassen, Klieverda, Madi, Martin, Morison, Morrison, Newburn, Ng, Oakley, Oakley, Oakley, Oakley, Olsen, Olsen, O’Cathain, Peel, Rebecca Shaw, Simonds, Singh, Springer, Stanworth, Tew, Tew, Thomas, Viisainen, Wertz   +53 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

How do pregnancy and birth experiences influence planned place of birth in future pregnancies? Findings from a longitudinal, narrative study. [PDF]

, 2015
A perception that first birth is more risky than subsequent births has led to women planning births in Obstetric Units, and care providers supporting these choices.
Fulop, NJ
core  

Health education and postpartum depression: exploring associations in clinical data

Frontiers in Psychiatry
BackgroundPostpartum depression is a common maternal mental health condition. Existing treatments, such as cognitive behavioral therapy and pharmacological interventions, often face challenges related to cost, accessibility, and acceptability ...
Xianfang Song, Zhengli Kang, Manting Sha, Sha Wang   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Birth size and breast cancer risk: Re-analysis of individual participant data from 32 studied [PDF]

, 2008
Background Birth size, perhaps a proxy for prenatal environment, might be a correlate of subsequent breast cancer risk, but findings from epidemiological studies have been inconsistent.
Collaborative, GOP-NRFASROBC, De Stavola, B, Dos Santos Silva, I, McCormack, V   +3 more
core  

Early life factors and risk of childhood rhabdomyosarcoma. [PDF]

, 2013
Although little is known about etiology of childhood rhabdomyosarcoma (RMS), early life factors are suspected in the etiology. We explored this hypothesis using linked data from the California Cancer Registry and the California birth rolls.
Anshu eShrestha, Anshu eShrestha, Beate eRitz, Christina A Lombardi, Julia eHeck, Michelle eWilhelm, Simona eOgnjanovic   +6 more
core   +2 more sources