Results 61 to 70 of about 33,358 (259)

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Sub-registro de nascimento: aspectos educativos visando à sua diminuição Omission of birth certificate: some educative aspects for its reduction

Revista de Saúde Pública, 1973
São analisadas as causas que podem condicionar a ocorrência de sub-registros de nascimento, isto é, omissões de declaração de nascimento e propostas medidas visando à sua diminuição. Algumas causas envolvem alterações legislativas e outras dizem respeito
Maria Helena Silveira, Maria Lucia Soboll   +1 more
doaj   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Kiedy naprawdę urodził się Leśmian. O metryce i innych nieznanych dokumentach

Teksty Drugie, 2017
We had no certainty about Bolesław Leśmian’s date of birth until his birth certificate was found at the State Archive in Warsaw. The document corroborates the date listed on the poet’s conversion certificate: he was born on Chmielna Street in Warsaw on ...
Dorota Samborska-Kukuć
doaj  

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Book review: Egzamin na tłumacza przysięgłego. Tłumaczenie odpisów aktów stanu cywilnego. Język francuski [The Sworn Translator Examination: translation of excerpts from Civil Status Records in the French Language]

Językoznawstwo
The book Egzamin na tłumacza przysięgłego. Tłumaczenie odpisów aktów stanu cywilnego. Język francuski [The Sworn Translator Examination: Translation of Excerpts from Civil Status Records in the French Language] explores practical aspects of legal ...
Maksymilian Bartoszewski
doaj   +1 more source

The use of database linkage technique for the improvement of information on mother-infant deaths in Ceara, 2006 [PDF]

Revista Brasileira em Promoção da Saúde, 2009
Objective: To assess the use of database linkage technique on the improvement of information on mother-infant deaths by recovering not registered and/or ignored variables from the deaths of children under one year old, in the city of Fortaleza, in 2006 ...
Augediva Maria Jucá Pordeus, Nádia Maria Girão Saraiva de Almeida, Luciano Pamplona de Góes Cavalcanti, José Gomes Bezerra Filho, Lindélia Sobreira Coriolano   +4 more
doaj  

Health plan administrative records versus birth certificate records: quality of race and ethnicity information in children

BMC Health Services Research, 2010
Background To understand racial and ethnic disparities in health care utilization and their potential underlying causes, valid information on race and ethnicity is necessary.
Chen Wansu, Jacobsen Steven J, Strickland Daniel, Getahun Darios T, Langer-Gould Annette, Iyer Rajan L, Smith Ning, Derose Stephen F, Koebnick Corinna   +8 more
doaj   +1 more source

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source