Results 51 to 60 of about 312,879 (216)

Serum Zinc Level at Term Pregnancy and Newborn Anthropometry

open access: yesIndonesian Journal of Obstetrics and Gynecology, 2015
Objective: To determine the relationship between serum zinc level at term pregnancy and newborn anthropometry. Methods: This study is an observational study with cross-sectional design.
Irma Seriana   +2 more
doaj   +1 more source

Antenatal maternal emotional distress and duration of pregnancy. [PDF]

open access: yesPLoS ONE, 2014
OBJECTIVE(S): We sought to prospectively study the association between antenatal emotional distress and gestational length at birth as well as preterm birth.
Mirjam Lukasse   +3 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Longitud y peso al nacer: el papel de la nutrición materna Weight and lenght at birth: The role of maternal nutrition

open access: yesSalud Pública de México, 1998
Objetivo. Identificar los factores determinantes del peso (PN) y la longitud al nacer (LN). Material y métodos. Se estudiaron 481 mujeres con sus neonatos, y se ajustaron modelos de regresión múltiple para PN y LN de acuerdo con un modelo biológico ...
TERESA GONZÁLEZ-COSSÍO   +4 more
doaj  

DISTRIBUTIONS OF ANTHROPOMETRIC MEASUREMENTS OF NEW BORN BABIES AMONG VARIOUS ETHNIC GROUPS IN MAIDUGURI, NIGERIA: A PROSPECTIVE STUDY [PDF]

open access: yesKanem Journal of Medical Sciences, 2014
Background: Weight and other newborn anthropometric measurements at birth are considered as the most important indicators of a newborn's chances of survival, growth, long-term health and psychosocial development.
Takai IU   +4 more
doaj  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

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