Results 71 to 80 of about 10,848,572 (295)
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Effects of birth order and sibling sex composition on human capital investment in children in India [PDF]
The paper explores the effects of birth order and sibling sex composition on human capital investment in children in India using the Indian Human Development Survey (IHDS).
Makino, Momoe
core
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Gender Differences in Schooling Attainment: The Role of Sibling Characteristics and Birth Order Effects [PDF]
This paper uses a using a nationally representative dataset to show that gender, birth order and sibling characteristics have significant effects on the schooling attainment of Egyptian children.
Dancer, Diane M., Rammohan, Anu
core
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Do birth order and family size matter for intergenerational income mobility? Evidence from Sweden [PDF]
Previous studies of intergenerational income mobility have not considered potential birth-order or family-size effects in the estimated income elasticity.
Lindahl, Lena
core
FACETSThe objective of the present systematic review was to incorporate previous studies investigating the association of birth order with the risk of systolic and diastolic blood pressure (DBP).
Danial Habibi +9 more
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Child Work and Schooling in Bangladesh: The Role of Birth Order [PDF]
Using data from Bangladesh, this paper examines how the birth order of a child influences parental decisions to place children in one of the four activities – ‘study only’, ‘study and work’, ‘neither work nor study’ and ‘work only’.
Rahman, Mohammad Mafizur +1 more
core