Results 91 to 100 of about 196 (191)

A Personal Perspective on Metalloprotein Structure and the Future of Macromolecular X‐Ray Crystallography

Journal of the Chinese Chemical Society, EarlyView.
While X‐ray crystallography has been the primary method for determining the structures of metalloproteins, cryoEM has taken over this role, illustrated by [4Fe4S]‐cluster containing proteins deposited in the Protein Data Bank. What will be the role for X‐ray crystallography as cryoEM and machine learning methods dominate the initial structural analysis?
Douglas C. Rees
wiley   +1 more source

The pandemic generation: Investigating the long‐term impact of a large‐scale stressor on the anxiety of children

JCPP Advances, EarlyView.
Abstract Background As a large‐scale global stressor, the COVID‐19 pandemic has a substantial impact on the mental health of children and adolescents. In this longitudinal study we investigate long‐term trajectories of anxiety of children during and after the pandemic (April 2020–April 2023), and identify associated risk factors. Methods A total of 514
Michiel A. J. Luijten, Hedy A. van Oers, Jacintha M. Tieskens, Marlene A. Werner, Josjan Zijlmans, Lotte Haverman, Tinca J. C. Polderman, Lianne P. de Vries   +7 more
wiley   +1 more source

Augmented Reality of Anatomical Structures of the Maxillomandibular Complex for Learning Dental Radiographic Techniques

Journal of Dental Education, EarlyView.
ABSTRACT Introduction Augmented reality (AR) enables interactive learning in real‐world environments. In dental radiography education, AR offers a promising tool to enhance students' clinical skills by allowing them to simulate and practice procedures before engaging with actual patients. Repeated practice in an AR environment can reinforce theoretical
Maitê Michel Piazza Willig, Mariana Boessio Vizzotto, Henrique Timm Vieira, Priscila Fernanda da Silveira Tiecher, Thiago de Oliveira Gamba, Nádia Assein Arús, Luis Ernesto Arriola‐Guillén, Heraldo Luís Dias da Silveira   +7 more
wiley   +1 more source

Simulation‐Based Learning in Oral Radiology: Students’ Perceptions of Training in Intraoral Radiographic Techniques Across Two Dental Institutes

Journal of Dental Education, EarlyView.
ABSTRACT Objective Simulation‐based learning (SBL) in oral radiology offers a safe, structured environment that supports students’ transition to clinical practice. However, limited research has captured students' perceptions of SBL for intraoral radiography training.
Abeer A. Almashraqi, Ankur Jethlia, Rebecca Glanville, Hanin Daas, Kamran Ali   +4 more
wiley   +1 more source

Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira, Caíque Olegário Diniz e Magalhães, Elizabeth Luciana Marinho Miguel, Larissa Vieira Toledo, Débora Ribeiro Orlando, Alan Rodrigues Teixeira Machado, Bruno Del Bianco Borges, Luciano José Pereira, Marco Fabrício Dias‐Peixoto, Eric Francelino Andrade   +9 more
wiley   +1 more source

Evaluating the Local Response of a Novel Injectable Capsule for Drug Delivery in the Trachea

The Laryngoscope, EarlyView.
A novel PLGA polymer capsule was developed for localized pretracheal drug delivery and evaluated for short‐term local tissue safety in a rabbit model. Implant placement was confirmed by ultrasound and was well tolerated over 14 days, with preservation of airway patency, native tracheal architecture, and biomechanical properties.
Denzel Ryan D. Cruz, Nour Awad, Nicholas Russell, Juliana El Sheikh, Logan Obermeyer, Peter J. Larson, Yoonjee C. Park, Gregory R. Dion   +7 more
wiley   +1 more source

Soft Tissue Safety Assessment of Pulsed Solid‐State Thulium:YAG Versus Holmium:YAG Lasers: A Quantitative Porcine Model Simulation

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives Laser lithotripsy carries an inevitable risk of collateral tissue injury. This study compared the safety profiles of pulsed Holmium:YAG and Thulium:YAG lasers by examining their effects on soft tissue under laser settings relevant to lithotripsy, using ex vivo porcine kidney models.
Dennis Buente, Rodrigo Suarez‐Ibarrola, Shane O'Sullivan, Arkadiusz Miernik, Ralf Petzold   +4 more
wiley   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

17O Quadrupole Coupling Constants in Water

Magnetic Resonance in Chemistry, EarlyView.
In water clusters, first‐nearest‐neighbor interactions (1A and 1D) provide the largest contribution and are well captured by an additive donor–acceptor scheme, with improved accuracy upon inclusion of hydrogen bond distance dependence. Second nearest neighbor (D and A*) effects introduce smaller but systematic negative corrections, restoring near ...
Nabeeha Haque, Alexander G. de Dios, Angel C. de Dios   +2 more
wiley   +1 more source

Information Design for Early‐Stage Dose‐Finding Trials

Naval Research Logistics (NRL), EarlyView.
ABSTRACT To enhance enrollment rates in early‐stage dose‐finding clinical trials, we propose an information design approach, where the clinical investigator (CI) commits to an information releasing mechanism (IRM) based on the treatment's uncertain efficacy and toxicity to encourage patients to participate in the trial.
Amin Khademi, Ningyuan Chen
wiley   +1 more source