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Monitoring of bisoprolol fumarate stability under different stress conditions
2017Stability studies of drugs by stress study is a very important process which is done by treating the study drug with different stress agents, with the aim to define the critical factors affecting the stability of the drug, to accurately define the storage conditions of the drug, as well as to identify the resulting degradation products.
Kasagić-Vujanović, Irena +2 more
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Degradation of Bisoprolol Fumarate in Tablets Formulated with Dicalcium Phosphate
Drug Development and Industrial Pharmacy, 1995Degradation of Bisoprolol Fumarate in tablet dosage forms was accelerated when granular Dicalcium Phosphate Anhydrous USP was substituted for milled Dicalcium Phosphate Anhydrous USP.
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Journal of Pharmaceutical and Biomedical Analysis, 2010
A simple, precise and stability-indicating HPLC method was developed and validated for the simultaneous determination of bisoprolol fumarate and hydrochlorothiazide in pharmaceutical dosage form. The method involves the use of easily available inexpensive laboratory reagents. The separation was achieved on an Inertsil ODS 3V (25cmx4.6mm) 5microm column
Sneha J, Joshi +4 more
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A simple, precise and stability-indicating HPLC method was developed and validated for the simultaneous determination of bisoprolol fumarate and hydrochlorothiazide in pharmaceutical dosage form. The method involves the use of easily available inexpensive laboratory reagents. The separation was achieved on an Inertsil ODS 3V (25cmx4.6mm) 5microm column
Sneha J, Joshi +4 more
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Spectrophotometric method for estimation of bisoprolol fumarate in tablets.
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 2014Bisoprolol fumarate is prescribed for the treatment of hypertension and angina pectoris.The purpose of this study was to develop a simple, sensitive, accurate, and reproducible method for estimation of bisoprolol fumarate in tablets.The proposed method was based on a yellow colored complex formed with tropaeolin 00, extractable in dichloromethane with ...
Alina Diana, Panainte +5 more
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Bisoprolol Fumarate: An Exploration on its Properties and Analytical Methods
Palestinian Medical and Pharmaceutical JournalCardiovascular diseases stay ahead and are the zenith reason for global death, with a pro-jected number of 17.9 million deaths in 2016 (i.e. 31% of global deaths). One of the third important threat cause of cardiovascular mortality is hypertension (high blood pressure). The US Food and Drug Organization (FDA) supported the use of Bisoprolol fumarate as
Manoj Verma +4 more
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Development and Evaluation of Bilayer Tablets of Bimodal release of Bisoprolol Fumarate
Research Journal of Pharmaceutical Dosage Forms and TechnologyBisoprolol is a type of antihypertensive drug (β-blocker). It is a poorly water-soluble and highly permeable drug that belongs to class II biopharmaceutical classification. This investigation represents the formulation development of bisoprolol to immediate and sustained the drug release.
Vinay R. Kothawade +2 more
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Preparation of bisoprolol fumarate nasal spray and its nasal delivery in rats.
Pakistan journal of pharmaceutical sciences, 2016The aim of the present work was to prepare a nasal spray of bisoprolol fumarate (BF). The Pharmacokinetics and relative bioavailability of the BF nasal formulation were evaluated in Wistar rats. The BF nasal spray after administration exhibited very fast absorption and higher plasma drug concentration.
Gu, Fugen +4 more
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Pakistan journal of pharmaceutical sciences, 2008
Two analytical methods have been developed for simultaneous quantification of bisoprolol fumarate and hydrochlorothiazide in combined pharmaceutical dosage form using spectrophotometer. Excellent simplicity, accuracy, precision and economy were achieved by the assay.
Shirkhedkar Atul, A +2 more
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Two analytical methods have been developed for simultaneous quantification of bisoprolol fumarate and hydrochlorothiazide in combined pharmaceutical dosage form using spectrophotometer. Excellent simplicity, accuracy, precision and economy were achieved by the assay.
Shirkhedkar Atul, A +2 more
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Current Computer-Aided Drug Design
Background: An important characteristic of the quality-by-design approach is defining risk, which is a combination of the probability of harm and its severity. During risk assessment, it is essential to determine how the formulation, properties of active ingredients and excipients, and process parameters can ...
Nadia Malanchuk +3 more
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Background: An important characteristic of the quality-by-design approach is defining risk, which is a combination of the probability of harm and its severity. During risk assessment, it is essential to determine how the formulation, properties of active ingredients and excipients, and process parameters can ...
Nadia Malanchuk +3 more
openaire +2 more sources