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Biowaiver Monograph for Immediate-Release Solid Oral Dosage Forms: Bisoprolol Fumarate

Journal of Pharmaceutical Sciences, 2014
Literature data relevant to the decision to allow a waiver of in vivo bioequivalence (BE) testing for the approval of immediate-release (IR) solid oral dosage forms containing bisoprolol as the sole active pharmaceutical ingredient (API) are reviewed.
Charoo, NA   +10 more
openaire   +3 more sources

Incompatibility of Bisoprolol Fumarate with Some Super-disintegrating Agents

British Journal of Pharmaceutical Research, 2015
Aims: Bisoprolol fumarate, a selective β1adrenoreceptor blocker, is usually formulated as immediate release tablet dosage form. While developing the immediate release tablet formula in laboratory, the assay and dissolution results were found below acceptance limit in some formulation. The formulations differed only in disintegrating agents. Therefore a
Abu Shakar   +4 more
openaire   +1 more source

SIMULTANEOUS ESTIMATION OF IVABRADINE HCl AND BISOPROLOL FUMARATE BY UV-SPECTROSCOPIC METHOD

GLOBAL JOURNAL FOR RESEARCH ANALYSIS, 2022
A simple UV spectrophotometric analytical method has been developed for simultaneous estimation of Ivabradine HCl and Bisoprolol used in the treatment of angina pectoris. Modied simultaneous equation method was developed with double beam UV-Visible spectrophotometer using water as a solvent.
Pushpak Pandit   +5 more
openaire   +1 more source

Monitoring of bisoprolol fumarate stability under different stress conditions

2017
Stability studies of drugs by stress study is a very important process which is done by treating the study drug with different stress agents, with the aim to define the critical factors affecting the stability of the drug, to accurately define the storage conditions of the drug, as well as to identify the resulting degradation products.
Kasagić-Vujanović, Irena   +2 more
openaire   +2 more sources

Degradation of Bisoprolol Fumarate in Tablets Formulated with Dicalcium Phosphate

Drug Development and Industrial Pharmacy, 1995
Degradation of Bisoprolol Fumarate in tablet dosage forms was accelerated when granular Dicalcium Phosphate Anhydrous USP was substituted for milled Dicalcium Phosphate Anhydrous USP.
openaire   +1 more source

Spectrophotometric method for estimation of bisoprolol fumarate in tablets.

Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 2014
Bisoprolol fumarate is prescribed for the treatment of hypertension and angina pectoris.The purpose of this study was to develop a simple, sensitive, accurate, and reproducible method for estimation of bisoprolol fumarate in tablets.The proposed method was based on a yellow colored complex formed with tropaeolin 00, extractable in dichloromethane with ...
Alina Diana, Panainte   +5 more
openaire   +1 more source

Development and Evaluation of Bilayer Tablets of Bimodal release of Bisoprolol Fumarate

Research Journal of Pharmaceutical Dosage Forms and Technology
Bisoprolol is a type of antihypertensive drug (β-blocker). It is a poorly water-soluble and highly permeable drug that belongs to class II biopharmaceutical classification. This investigation represents the formulation development of bisoprolol to immediate and sustained the drug release.
Vinay R. Kothawade   +2 more
openaire   +1 more source

Preparation of bisoprolol fumarate nasal spray and its nasal delivery in rats.

Pakistan journal of pharmaceutical sciences, 2016
The aim of the present work was to prepare a nasal spray of bisoprolol fumarate (BF). The Pharmacokinetics and relative bioavailability of the BF nasal formulation were evaluated in Wistar rats. The BF nasal spray after administration exhibited very fast absorption and higher plasma drug concentration.
Gu, Fugen   +4 more
openaire   +1 more source

Simultaneous spectrophotometric estimation of Bisoprolol fumarate and hydrochlorothiazide in tablet dosage form.

Pakistan journal of pharmaceutical sciences, 2008
Two analytical methods have been developed for simultaneous quantification of bisoprolol fumarate and hydrochlorothiazide in combined pharmaceutical dosage form using spectrophotometer. Excellent simplicity, accuracy, precision and economy were achieved by the assay.
Shirkhedkar Atul, A   +2 more
openaire   +1 more source

Prediction Factors for Quality Risks in the Pharmaceutical Developmentof Tablets Bisoprolol Fumarate with Indapamide

Current Computer-Aided Drug Design
Background: An important characteristic of the quality-by-design approach is defining risk, which is a combination of the probability of harm and its severity. During risk assessment, it is essential to determine how the formulation, properties of active ingredients and excipients, and process parameters can ...
Nadia Malanchuk   +3 more
openaire   +2 more sources

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