Background: This study aims to investigate the effect of fixed orthodontic appliances and/or antihypertensive drugs on the weight of experimental rats.
Hadeel A Mahdi +2 more
doaj +1 more source
Toxicological and ecotoxicological risk‐based prioritization of pharmaceuticals in the natural environment [PDF]
Approximately 1500 active pharmaceutical ingredients are currently in use; however, the environmental occurrence and impacts of only a small proportion of these have been investigated.
Agerstrand +37 more
core +1 more source
A REVIEW ON ANALYTICAL METHOD FOR THE ESTIMATION OF TELMISARTAN AND BISOPROLOL FUMARATE
openalex +2 more sources
The aim of this work was the development of an efficient analytical method for the determination of bisoprolol and related substances in the finished drug product using HPLC/DAD.
Elena Lazarevska Todevska +2 more
doaj +1 more source
Istodobno spektrofotometrijsko određivanje losartan kalija, amlodipin besilata i hidroklorotiazida u farmaceutskim pripravcima kemometrijskom metodom [PDF]
In the present work, four different spectrophotometric methods for simultaneous estimation of losartan potassium, amlodipine besilate and hydrochlorothiazide in raw materials and in formulations are described.
A. Sankar +26 more
core +2 more sources
The Maillard reaction of bisoprolol fumarate with various reducing carbohydrates
HPLC analysis of drug products containing bisoprolol fumarate and lactose revealed the presence of N-formylbisoprolol, which is a final product of the Maillard reaction. Formulations containing secondary amines and reducing carbohydrates are prone to the condensation of amine and carbonyl functional groups and formation of glycosylamines in ...
Mateusz, Szalka +4 more
openaire +2 more sources
An observational study of Donor Ex Vivo Lung Perfusion in UK lung transplantation: DEVELOP-UK [PDF]
Background: Many patients awaiting lung transplantation die before a donor organ becomes available. Ex vivo lung perfusion (EVLP) allows initially unusable donor lungs to be assessed and reconditioned for clinical use.
Andreasson +102 more
core +4 more sources
Beta-cyclodextrin (BCD) has been used as electroactive material for preparing carbon paste electrodes (CPEs) selective for bisoprolol fumarate (BPF). The paste incorporating BCD, graphite, and o-NPOE as a solvent mediator in weight percent ratio (1.4:69 ...
Eman Yossri Frag +3 more
doaj +1 more source
DEVELOPMENT AND VALIDATION OF HPLC-DAD METHOD FOR THE DETERMINATION OF BISOPROLOL IN TABLET DOSAGE FORMS [PDF]
Objective: A rapid, simple and sensitive RP-HPLC method was developed and validated for the determination of bisoprolol fumarate in bulk and pharmaceutical dosage form. Methods: Chromatographic separation was achieved within 2.5 min on ACQUITY Arc System,
Abdel-Megied, Ahmed +5 more
core +3 more sources
HPLC METHOD DEVELOPMENT FOR THE ANALYSIS OF BISOPROLOL IN COMBINED DOSAGE FORM CONTAINING BISOPROLOL AND ENALAPRIL AND IN VITRO DISSOLUTION STUDIED [PDF]
Objective: A simple, rapid and reproducible HPLC method was developed for the determination of bisoprolol in experimental combined dosage forms containing bisoprolol and enalapril and for drug dissolution studies. Methods: A C18 column (Hi Qsil C18, 5 μm,
Abdel-Megied, Ahmed M. +6 more
core +3 more sources

