Results 251 to 260 of about 38,540 (306)

Mechanisms of Resistance to Novel Immunotherapies in B-Cell Lymphomas: Focus on CAR T and Bispecific Antibodies. [PDF]

Cancers (Basel)
Arena G, Chiarle R.
europepmc   +1 more source

Hematopoietic progenitor kinase-1 inhibition improves the in vitro efficacy of bispecific antibodies in CLL. [PDF]

Blood Adv
Shorer Arbel Y, Yitzhak L, Katz BZ, Herishanu Y.   +3 more
europepmc   +1 more source

High-affinity transferrin receptor binding improves brain delivery of bispecific antibodies at tracer dose. [PDF]

Fluids Barriers CNS
Bonvicini G, Singh S, Sandersjöö L, Dallas T, Schlein E, Dahlén AD, Lopes van den Broek S, Sehlin D, Andersson KG, Syvänen S.   +9 more
europepmc   +1 more source

Bispecific antibodies combined with chemotherapy in solid tumor treatment, the path forward? [PDF]

Front Immunol
Yan Y, Yuan J, Peng Y, Zhou C, Liu X, Sun L, Song Q.   +6 more
europepmc   +1 more source

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Engineering bispecific antibodies

Current Opinion in Biotechnology, 1993
Bispecific antibodies have immense potential as reagents and in medicine. Until recently, they were made by combining monoclonal antibodies of two different specificities in vitro, or by fusion of the corresponding hybridomas. Protein engineering now offers the chance to construct a range of small 'designer' bispecific antibodies using antibody ...
P, Holliger, G, Winter
openaire   +2 more sources

Bispecific antibodies: design, therapy, perspectives

Drug Design, Development and Therapy, 2018
Antibodies (Abs) containing two different antigen-binding sites in one molecule are called bispecific. Bispecific Abs (BsAbs) were first described in the 1960s, the first monoclonal BsAbs were generated in the 1980s by hybridoma technology, and the first article describing the therapeutic use of BsAbs was published in 1992, but the number of papers ...
Sergey Sedykh, Valentina Buneva, Georgy A Nevinsky   +2 more
exaly   +5 more sources

Bispecific Antibodies in Lymphoma

International Reviews of Immunology, 1993
Journal Article ; Review ; SCOPUS: ar.j ; info:eu-repo/semantics ...
Brissinck, J, Demanet, Christian, Moser, Muriel, Leo, Oberdan, Thielemans, Kris   +4 more
openaire   +2 more sources

Production of Bispecific Antibodies

Current Protocols in Immunology, 1995
AbstractBispecific antibodies (bsAbs) contain two different binding specificities within a single molecule and can specifically bind two different molecules together. BsAbs can be produced by chemically cross‐linking purified antibodies or Fab fragments with reducible disulfide bonds or nonreducible thioether bonds, both of which are described in this ...
David M, Segal, Bert J E G, Bast
openaire   +2 more sources