Melatonin restores testosterone production in aging Leydig cells by targeting key pathological drivers, particularly oxidative stress and mitochondrial dysfunction. This approach offers a fundamental strategy to reshape the Late‐onset hypogonadism treatment paradigm.
Hui Wu +6 more
wiley +1 more source
Bisphenol a and polycystic ovary syndrome in reproductive-age women: mechanistic exploration via network toxicology and molecular docking. [PDF]
Peng C, Wang C, Chen J, Chen H.
europepmc +1 more source
Contact Sensitization in Adults With Atopic Dermatitis: A 21‐Year Single‐Center Tertiary Experience
A graphical abstract has been included as supplemental material. ABSTRACT Background Atopic dermatitis is a common chronic inflammatory skin condition. Data on contact sensitization in adults with atopic dermatitis remain limited. Objectives To investigate the prevalence of contact sensitization in adults with and without AD: Patients/Methods A ...
Francesca Caroppo +5 more
wiley +1 more source
Microplastic Impacts on Seafood: A Global Synthesis of Experimental Findings
ABSTRACT Plastic pollution is a growing global concern, with plastic and microplastic particles now widespread in aquatic environments. Microplastics are frequently ingested by marine organisms, including commercially important seafood species. Ingestion can lead to a range of biological effects, influenced by the size, type and quantity of plastic, as
Nina Wootton +4 more
wiley +1 more source
Abstract The objective of this work is to assess the effects and potential process of paternal acute sleep deprivation on cardiac function in their offspring. Male and female C57BL/6N mice aged 8–9 weeks (n = 4–5 mice/group) were used. Male mice were selected to construct an acute sleep deprivation model using the modified multiple platform method ...
Yingying Zhang +12 more
wiley +1 more source
Bisphenol A disrupts cartilage homeostasis through CYP2C19. [PDF]
Bai Y, Feng K, Niu T, Bai X, Chen Z.
europepmc +1 more source
Chemical lignin stabilization during acid hydrotropic fractionation is shown to distinctly influence delignification, lignin quality, and pulp performance. Phenol enhances lignin removal, while thiol‐based modifier yields light‐colored lignin, high recovery, and strong pulp.
Juho Antti Sirviö +7 more
wiley +1 more source
Enhancing Interfacial and Mechanical Properties of Carbon Fiber/Poly (Ether Ether Ketone) Composites via Bisphenol-Based Polyimide Modification. [PDF]
Albayrak A, Dogu M, Cakir M, Turhan K.
europepmc +1 more source
Directed Evolution of an Efficient Polycarbonate Depolymerase With Exceptional Operational Stability
Here, we show that well studied PET hydrolases can be re‐engineered via directed evolution to deconstruct alternative aromatic‐containing commodity polymers. Introduction of only three mutations into LCCICCG was sufficient to generate an efficient polycarbonate hydrolase with high operational stability that can fully depolymerize a polycarbonate sample
Henry A. Jones +7 more
wiley +1 more source
Migration of Bisphenol A and Its Derivatives From Epoxy Coatings and Demand for BPA-NI Products: Scientific Insights and Perspectives Leading to Regulation (EU) 2024/3190. [PDF]
Kajiyama T +4 more
europepmc +1 more source

