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Genotoxic activity of bisphenol A and its analogues bisphenol S, bisphenol F and bisphenol AF and their mixtures in human hepatocellular carcinoma (HepG2) cells

Science of The Total Environment, 2019
The use of bisphenol A (BPA) in manufacturing of plastics is being gradually replaced by presumably safer analogues such as bisphenol S (BPS), bisphenol F (BPF) and bisphenol AF (BPAF). Despite their widespread occurrence in the environment, there is a knowledge gap in their toxicological profiles. We investigated cytotoxic/genotoxic effects as well as
Klara Hercog   +5 more
openaire   +2 more sources

Bisphenol A and its analogue bisphenol S exposure reduce estradiol synthesis via the ROS-mediated PERK/ATF4 signaling pathway

Food and Chemical Toxicology, 2023
As a kind of endocrine-disrupting chemicals, BPA may affect the human placenta. Due to consumer unease about BPA, many manufacturers are using alternatives to BPA, such as BPS. However, some reports suggest that BPS may produce similar results to BPA. To understand how BPA/BPS leads to reduced synthesis of placental estradiol (E2), we conducted studies
Zhou, Li   +9 more
openaire   +2 more sources

Prenatal exposure to bisphenol a and its analogues (bisphenol F and S) and ultrasound parameters of fetal growth

Chemosphere, 2020
Bisphenol A (BPA) has been shown to affect normal fetal growth, but human evidence on its analogues (BPF and BPS) is limited.To examine the associations between prenatal exposure to BPA and its analogues (BPF and BPS) and ultrasound parameters of fetal growth.We measured urinary BPA, BPF, and BPS concentrations among 322 pregnant women during late ...
Bin, Zhou   +5 more
openaire   +2 more sources

Biodegradation of bisphenol A and its halogenated analogues by Cunninghamella elegans ATCC36112

Biodegradation, 2010
Bisphenol A and its halogenated analogues are commonly used industrial chemicals with strong toxicological effects over many organisms. In this study, metabolic fate of bisphenol A and its halogenated analogues were evaluated with Cunninghamella elegans ATCC36112. Bisphenol A and related analogues were rapidly transformed into several metabolites by C.
Young Soo, Keum   +3 more
openaire   +2 more sources

Binding of Bisphenol-F, a bisphenol analogue, to calf thymus DNA by multi-spectroscopic and molecular docking studies

Chemosphere, 2017
BPF (Bisphenol-F), a member of the bisphenol family, having a wide range of industrial applications is gradually replacing Bisphenol-A. It is a recognized endocrine disrupting chemical (EDC). EDCs have been implicated in increased incidences of breast, prostate and testis cancers besides diabetes, obesity and decreased fertility.
Afia, Usman, Masood, Ahmad
openaire   +2 more sources

Synthetic polymers adsorbing bisphenol�A and its analogues prepared by covalent molecular imprinting using bisphenol�A dimethacrylate as a template molecule

Analytical and Bioanalytical Chemistry, 2004
Synthetic polymers which can adsorb bisphenol A (BPA) and related compounds were prepared by a covalent molecular imprinting technique. BPA dimethacrylate, used as template molecule, was polymerized with a crosslinker, triethylene glycol dimethacrylate (TEGDMA) or trimethylol propane trimethacrylate (TRIM).
Takashi, Ikegami   +3 more
openaire   +2 more sources

Resin-based dental sealants as a source of human exposure to bisphenol analogues, bisphenol A diglycidyl ether, and its derivatives

Environmental Research, 2018
Although studies have examined leaching of bisphenol A (BPA) from dental sealants into saliva, occurrence of BPA, bisphenol A diglycidyl ether (BADGE), and their derivatives in dental sealants themselves has not been investigated. In this study, concentrations of eight bisphenol analogues (BPs), BADGE and its derivatives (BADGEs), including BADGE‧H2O ...
Jingchuan, Xue   +4 more
openaire   +2 more sources

Dielectric Properties of Bisphenol A Polycarbonate and Its Tethered Nitrile Analogue

Macromolecules, 2013
The relative permittivity and dielectric strength have been determined for a bisphenol A polycarbonate (BPA-PC), in which a cyanoethyl group has been substituted for one of the geminal dimethyl groups. The new material (CN-PC) has a glass transition temperature that is 19 K higher than that for BPA-PC. In addition, the dielectric strength of CN-PC, 405
John T. Bendler   +6 more
openaire   +1 more source

Bisphenol A analogues bisphenol B, bisphenol F, and bisphenol S induce oxidative stress, disrupt daily sperm production, and damage DNA in rat spermatozoa: a comparative in vitro and in vivo study

Toxicology and Industrial Health, 2019
Bisphenol A (BPA) is a well-known endocrine-disrupting chemical with estrogenic activity. The widespread exposure of individuals to BPA is suspected to affect a variety of physiological functions, including reproduction, development, and metabolism. Here we report the mechanisms by which BPA and three of its analogues bisphenol B (BPB), bisphenol F ...
Asad, Ullah   +4 more
openaire   +2 more sources

Bisphenol A Analogues Induce Neuroendocrine Disruption via Gut–Brain Regulation in Zebrafish

Environmental Science & Technology
There is epidemiological evidence in humans that exposure to endocrine-disrupting chemicals such as bisphenol A (BPA) is tied to abnormal neuroendocrine function with both behavioral and intestinal symptoms. However, the underlying mechanism of this effect, particularly the role of gut-brain regulation, is poorly understood.
Xiyan Mu   +9 more
openaire   +2 more sources

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