Results 111 to 120 of about 827 (246)

Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis

Advanced Science, EarlyView.
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley   +1 more source

Versatile On-Chip Programming of Circuit Hardware for Wearable and Implantable Biomedical Microdevices. [PDF]

Adv Sci (Weinh), 2023
Lee AH, Lee J, Leung V, Nurmikko A.
europepmc   +1 more source

Wavy‐Interlocked Stretchable Triboelectric Nanogenerators Enhanced by Liquid Metal Microflowers for Self‐Powered Wearable Motion Monitoring

Advanced Science, EarlyView.
Schematic showing a stretchable triboelectric nanogenerator based on interlocked wavy architectures that uses EGaIn microflower‐embedded PVDF‐TrFE and Nylon‐6 nanofiber membranes. The multi‐petaled, electron‐rich EGaIn microflowers enhance interfacial polarization and capacitance, while the interlocked wavy architecture enlarges the effective contact ...
Qianqian Xu, Huimin Li, Hanmin Zeng, Yahui Meng, Yimeng He, Xinke Hu, Senfeng Zhao, Jianxun Zhang, Peiqiong Zhou, Kechao Zhou, Dou Zhang, Chris Bowen, Yan Zhang   +12 more
wiley   +1 more source

A miniaturized implantable electrochemical platform for continuous monitoring of metabolites in deep tissue. [PDF]

Sci Adv
Madsen KE, Hintermueller D, Opel EA, Ribaudo JG, Saffari S, Cho S, Ciatti JL, Huang YT, Westman AM, Nuzzo RG, Pet MA, Rogers JA.   +11 more
europepmc   +1 more source

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

ANKS1B in the Nucleus Accumbens Controls Escalated Cocaine Self‐Administration via Regulating CBP‐FoxO3 Complex

Advanced Science, EarlyView.
ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang, Xiaoxuan Wu, Xuan Chen, Chao Peng, Zihang Li, Shumin Gao, Shiqiu Meng, Jing Dong, Dong Wu, Liying Lv, Ying Han, Yanxue Xue, Lin Lu, Jie Shi, Jianfeng Liu, Yan Sun   +15 more
wiley   +1 more source

Breaking the 2-nm Barrier in Hard Disk Drives Using Monolayer Amorphous Carbon Overcoats. [PDF]

Adv Mater
Zhang H, Grebenko AK, Litvinov D, Zheng W, Iakoubovskii KV, Grebenchuk SY, Makarova A, Fedorov A, Starkov A, Orofeo CM, Vyalikh DV, Lanza M, Koperski M, Novoselov KS, Toh CT, Ӧzyilmaz B.   +15 more
europepmc   +1 more source

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

Advanced Science, EarlyView.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth, Christoph F. Jacob, Alexandra Nguyen, Mandy Beyer, Andreas O. Mieland, Mario Dejung, Jia‐Xuan Chen, Walburgis Brenner, Christina Ehrhardt, Andreas Henke, Oliver H. Krämer   +10 more
wiley   +1 more source

On-patient medical record and mRNA therapeutics using intradermal microneedles. [PDF]

Nat Mater
Han J, Kanelli M, Liu Y, Daristotle JL, Pardeshi A, Forster TA, Karchin A, Folk B, Murmann L, Tostanoski LH, Carrasco SE, Alsaiari SK, Wang EY, Tran K, Zhang L, Eshaghi B, Levy L, Pyon S, Sloane C, Lin SQ, Lau A, Perkinson CF, Bawendi MG, Barouch DH, Durand F, Langer R, Jaklenec A.   +26 more
europepmc   +1 more source

Redox-enabled electronic interrogation and feedback control of hierarchical and networked biological systems. [PDF]

Nat Commun, 2023
Wang S, Chen CY, Rzasa JR, Tsao CY, Li J, VanArsdale E, Kim E, Zakaria FR, Payne GF, Bentley WE.   +9 more
europepmc   +1 more source