Results 41 to 50 of about 150,609 (316)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Oral flora of stray dogs and cats in Algeria: Pasteurella and other zoonotic bacteria [PDF]
Veterinary World, 2020 Background and Aim: Knowledge of potentially pathogenic bacteria presents in the oral cavity of dogs and cats may be helpful in determining appropriate treatment for infected bite wounds.
Kahina Razali +4 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Saudi Medical Journal, 2005 The aim of this study was to put forward a retrospective analysis of animal bites treated in our department.A total of 1315 patients treated in the Department of Plastic Reconstructive and Aesthetic Surgery of Ankara Education and Research Hospital, Ankara, Turkey between January 2002 and March 2004 are included in the study.
Dogan, Tuncali +3 more
openaire +2 more sources
Materials & DesignMetal additive manufacturing is a promising technology for the production of functional medical products, due to its high shape complexity and resolution, and ability to withstand sterilization temperatures.
Kirsten Lussenburg +3 more
doaj +1 more source
Fn14-targeted BiTE and CAR-T cells demonstrate potent preclinical activity against glioblastoma
OncoImmunology, 2021 T cell-engaging therapies involving bispecific T cell engager (BiTE) and chimeric antigen receptor T (CAR-T) cells have achieved great success in the treatment of hematological tumors.
Gaowei Li +12 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The Use of Sound Recorders to Remotely Measure Grass Intake Behaviour in Horses
AnimalsVisual observation to record grass intake is time-consuming and labour-intensive. Technological methods, such as activity monitors, have been used but only record head position.
Daisy E. F. Taylor +2 more
doaj +1 more source