Results 51 to 60 of about 172,827 (313)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Fn14-targeted BiTE and CAR-T cells demonstrate potent preclinical activity against glioblastoma
OncoImmunology, 2021 T cell-engaging therapies involving bispecific T cell engager (BiTE) and chimeric antigen receptor T (CAR-T) cells have achieved great success in the treatment of hematological tumors.
Gaowei Li +12 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
, 1959 Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about Marty Wallace, a Weatherford boy, being treated for a snake ...
WBAP-TV (Television station : Fort Worth, Tex.)
core +1 more source
The Use of Sound Recorders to Remotely Measure Grass Intake Behaviour in Horses
AnimalsVisual observation to record grass intake is time-consuming and labour-intensive. Technological methods, such as activity monitors, have been used but only record head position.
Daisy E. F. Taylor +2 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Case Report of a Newborn Injured By Human Bite
, 2015 Bite is a type of wound received from the teeth of an animal, including humans. Human bites are third leading cause of all bites after dog and cat bites.
Emel Ataoğlu +4 more
core +1 more source
The impact of sound-bite journalism on public argument [PDF]
, 2016 The rise of sound-bite news is one of the most widely bemoaned findings in political communication research. Yet, the detrimental effects of this trend have been more assumed than demonstrated. This study examines one consequence of sound-bite journalism:
Rinke, EM, Rinke, Eike Mark
core +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source