Results 71 to 80 of about 151,101 (316)
The Discretion Licensing of Gambling by Municipality: the Balance between Residents and Entrepreneur’s Interests [PDF]
, 2017 Latvijā ir attīstīts azartspēļu bizness. Minētās jomas attīstībā liela nozīme ir pašvaldībām, kuras izsniedz licences azartspēļu organizēšanai un jaunu spēļu zāļu atvēršanai. K.
Bite, Kitija
core +1 more source
Parasites & Vectors, 2012 Background Sandflies are vectors of Leishmania, the causative agent of leishmaniasis in mammalian hosts, including humans. The protozoan parasite is transmitted by the sandfly bite during salivation that occurs at the moment of blood feeding.
Secundino Nagila FC +5 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Novel Low-Cost Sensor for Human Bite Force Measurement [PDF]
, 2016 This paper presents the design and development of a low cost and reliable maximal voluntary bite force sensor which can be manufactured in-house by using an acrylic laser cutting machine.
Fastier-Wooller, Jarred +20 more
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Validation of the Arabic version of the brief irritability test (Ar-BITe) in non-clinical adolescents [PDF]
, 2023 Background: Despite the substantial clinical relevance of irritability in the development and maintenance of several mental disorders and its negative effects on functioning, no valid and reliable measures are available yet to identify the presence and ...
Obeid, Sahar +5 more
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
A cost-utility analysis of small bite sutures versus large bite sutures in the closure of midline laparotomies in the United Kingdom National Health Service [PDF]
, 2018 Shyam Ajay Gokani,1 Karl O Elmqvist,1 Osman El-Koubani,1 Javier Ash,1 Sudeep K Biswas,1 Maxime Rigaudy2 1Faculty of Medicine, Imperial College London, London, UK; 2Hull York Medical School, University of York, York, UK Purpose: This study aimed to ...
Biswas SK +5 more
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