Results 41 to 50 of about 48,770 (265)

Human Bite on Nose

Bengal Journal of Otolaryngology and Head Neck Surgery, 2019
Introduction Human bites are notorious due to chance of infection by direct inoculation of pathogens from saliva and must be managed properly. Human bite injuries cause dilemma to the treating doctor regarding its way of management.
Prasit Biswas, Shriyash Sinha, Somnath Saha   +2 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

The burden of bites and stings management: Experience of an academic hospital in the Kingdom of Saudi Arabia

Saudi Pharmaceutical Journal, 2020
Purpose: The main aim of this study is to estimate the economic burden and prevalence of bites and stings injuries in Saudi Arabia. Methods: A retrospective, cross-sectional study was conducted at King Saud University Medical City (KSUMC) for all bites ...
Anas Khan, Waad H. Al-Kathiri, Bander Balkhi, Osama Samrkandi, Mohammed S. Al-Khalifa, Yousef Asiri   +5 more
doaj   +1 more source

Presentation and treatment of animal and human bite injuries at a Swiss tertiary emergency department: a cross-sectional study

Swiss Medical Weekly, 2023
BACKGROUND: Animal and human bite injuries are a relevant health problem worldwide. With the increasing number of pets, bite injuries are becoming more frequent.
Simone Ehrhard, Mirjam Keller, Linda Morgenstern, Martin Müller, Meret E. Ricklin, Jolanta Klukowska-Rötzler, Aristomenis K. Exadaktylos, Dominik A. Jakob   +7 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Molecular Detection of Anaplasma phagocytophilum and Ehrlichia Species in Ticks Removed from Humans in the Republic of Korea

Microorganisms, 2022
Human granulocytic anaplasmosis (HGA) and human monocytic ehrlichiosis (HME) are zoonotic tick-borne diseases transmitted via tick bites. To determine the state of human Anaplasma and Ehrlichia infections caused by tick bites in the Republic of Korea ...
Yu-Jung Kim, Ji Ye Seo, Seong Yoon Kim, Hee Il Lee   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Epidemiology, clustering and spatial distribution of animal bites in Algeria

Journal of Biostatistics and Epidemiology
Introduction: Animals can transmit many viral and bacterial diseases through bites and saliva that can be potentially fatal to human. Rabies, one of these diseases, is rife in two-thirds of the world’s countries. Algeria is not spared.
Latifa Bouguerra, Mohamed L’Hadj, Schehrazad SELMANE   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Social animal bites in a non social way: A profile of human bite cases at GIMS, Kalaburagi (H-K region) [PDF]

Al Ameen Journal of Medical Sciences, 2018
Background: Human bites in human beings are important injuries that constitute one of the emergency visits to the General surgery department. Human bite injuries may lead to infection, loss of function, and interpersonal relation. Human bites are usually
Sangamesh B. Tondare, Shradha S. Maka, Ravindra Chimkode, Mahesh B. Tondare, E.R. Ashish   +4 more
doaj