Results 41 to 50 of about 2,678 (157)

Prenatal and postnatal exposures to four metals mixture and IQ in 6-year-old children:A prospective cohort study in South Korea

, 2021
BACKGROUND: Humans are exposed to a mixture of metals during their lifetime; however, evidence of neurotoxicity of such mixtures in critical time windows is still insufficient. We aimed to elucidate the associations of four metals mixture across multiple
Young Ah Lee, Yebin D. Ahn, Yoon-Jung Choi, Youn-Hee Lim, Kim, Johanna Inhyang, Choi, Yoon-Jung, Lee, Kyung-Shin, Kim, Kyoung-Nam, Lee, Young Ah, Hong, Yun-Chul, Shin, Choong Ho, Ahn, Yebin D, Yun-Chul Hong, Johanna Inhyang Kim, Jang, Yoonyoung, Kim, Bung-Nyun, Yoonyoung Jang, Kyoung-Nam Kim, Kyung-Shin Lee, Bung-Nyun Kim, Lim, Youn-Hee, Choong Ho Shin, Jinwoo Cho, Cho, Jinwoo   +23 more
core   +1 more source

Impact of mixtures of persistent organic pollutants on breast cancer aggressiveness

Environment International, 2022
Introduction: Breast cancer (BC) is frequent with a poor prognosis in case of metastasis. The role of the environment has been poorly evaluated in its progression.
Louise Benoit, Meriem Koual, Céline Tomkiewicz, Anne-Sophie Bats, Jean-Philippe Antignac, Xavier Coumoul, Robert Barouki, German Cano-Sancho   +7 more
doaj   +1 more source

A Stacking Ensemble Machine Learning Model for Predicting Vitamin D Deficiency in Bangladeshi Infants

Vector: The Journal of Engineering, Volume 2027, Issue 1, January/December 2027.
This study uses machine learning to predict vitamin D levels in Bangladeshi infants aged 12–24 months, addressing deficiency despite abundant sunlight. A stacking ensemble model combining Gaussian regressor, extra trees and XGBoost achieved the highest accuracy (R2$R^2$: 0.933, RMSE: 3.312).
Sadia Nasrin Tuly, Shatabdi Majumder, Koushik Roy, Md. Easin, Saha Reno, Golam Moktader Nayeem, Ahosan Habib, Atoshi Chowdhury   +7 more
wiley   +1 more source

Complex environmental contaminant mixtures and their associations with thyroid hormones using supervised and unsupervised machine learning techniques

Environmental Advances, 2021
Evaluating complex mixtures and their associated health effects poses a challenge in human populations. Herein, we assess the association between 17 organic and metal contaminants in blood with thyroid hormones in a remote Indigenous (First Nations ...
Eric N. Liberda, Aleksandra M. Zuk, David S. Di, Robert J. Moriarity, Ian D. Martin, Leonard J.S. Tsuji   +5 more
doaj   +1 more source

Practical considerations for characterization of the external exposome in Alzheimer's disease and related dementias cohorts

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract External exposome research offers opportunities to evaluate complex relationships between multiple environmental determinants of Alzheimer's disease and related dementias (ADRD). However, selecting specific exposure domains, identifying metrics, and downloading, processing, and managing big data are key challenges in translating the potential ...
Zachary Popp, Allison James, Marco Chivardi, Cameron J Reimer, Charlotte Robbins, Tara Jenson, Jeroen M van Baar, Peter James, Kevin J Lane, Marcia Pescador Jiménez   +9 more
wiley   +1 more source

Additional file 1 of An overview of methods to address distinct research questions on environmental mixtures: an application to persistent organic pollutants and leukocyte telomere length

, 2019
Supplemental description of methods and additional tables and figures. Table S1 Useful resources for included methods. Table S2 Overview of method characteristics. Table S3 POP characteristics. Table S4 Demographic Characteristics. Figure S1 Hierarchical
Ami R. Zota (1265484), Jeff Goldsmith (537662), Brent A. Coull (7536257), Elizabeth A. Gibson (1282035), Stefano Renzetti (5117225), Marianthi-Anna Kioumourtzoglou (1636114), Katrina L. Devick (6340886), Yanelli Nunez (7322855), Ahlam Abuawad (7322858), Chris Gennings (60838)   +9 more
core   +1 more source

Long-term exposure to PM_2.5 compositions and O₃ and their interactive effects on DNA methylation of peripheral brain-derived neurotrophic factor promoter

, 2023
This study examined the associations of long-term exposure to ambient fine particulate matter (PM2.5) compositions/ozone with methylation of peripheral brain-derived neurotrophic factor (BDNF) promoters.
Shanshan Li (114847), Guang-Hui Dong (347988), Ruqing Liu (75910), Zhaohuan Gui (4509766), Yuming Guo (162863), Bing Xie (234712), Yuewei Liu (170474), Lei Yang (102719), Haoyu Huang (12414634), Lijun Chen (313408), Gongbo Chen (9718660)   +10 more
core   +1 more source

Cord blood metal(loid) concentrations and bile acid profiles: Insights from mixture analysis

Ecotoxicology and Environmental Safety
Bile acids (BAs) are essential signaling molecules that regulate metabolic and inflammatory processes. However, epidemiological evidence on the influence of metal(loid) mixtures on BA profiles remains scarce, particularly among newborns.
Chuyi Ou, Dan Luo, Lihong Wu, Bibai Du, Di Liu, Jun Yang, Weixiang Wu   +6 more
doaj   +1 more source

Exposure to endocrine disrupting chemicals (EDCs) and cardiometabolic indices during pregnancy: The HOME Study

Environment International, 2021
Background: Toxicology studies have identified pregnancy as a window of susceptibility for endocrine disrupting chemicals (EDCs) and cardiometabolic indices in women.
Ann M. Vuong, Joseph M. Braun, Andreas Sjödin, Antonia M. Calafat, Kimberly Yolton, Bruce P. Lanphear, Aimin Chen   +6 more
doaj   +1 more source

Pesticide Residues, Gut Microbiota, and Gastrointestinal Outcomes: A Scoping Review of Human Evidence

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 5, September 2026.
ABSTRACT Vegetables anchor healthy‐diet recommendations yet are the principal nonoccupational route by which residues of organophosphate (OP), pyrethroid, neonicotinoid, organochlorine (OC), and glyphosate herbicide enter the diet, with the gut microbiota a plausible mediator linking these residues to functional gastrointestinal (GI) and inflammatory ...
Chengqian Ye, Qingjie Wu, Zhaochu Wang, Cai Zhang   +3 more
wiley   +1 more source