Results 51 to 60 of about 3,418,871 (244)

Black-start of remote areas through SCR-based HVDC Links

open access: yes, 2021
This paper analyses the possibility to black-start a remote area using an existing Line Commutated Converter HVDC link.To do this, a relatively small size Voltage Sourced Converter must be installed at the link receiving-end.
Sani L.   +7 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Editorial: March 2019 (Vol. 5, Issue 1)

open access: yes, 2019
Over the past year, we’ve had a change of hands from our founder, Matt Barr, to our new editor-in-chief, Mahli-Ann Butt. We’ve taken some extra time to put together this issue with great pride and care.
Thomson, Reece   +7 more
core   +3 more sources

Black-start strategy of distribution network considering photovoltaic output volatility and micro-grid synergy

open access: yesDiance yu yibiao
The fluctuation of photovoltaic output will cause the restored load to outage again. It is significant to exploit the dispatching resources of micro-grid to reduce load blackout loss of distribution network black-start and resist the risk of load loss ...
ZHONG Hao   +3 more
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Editorial: Negotiating Gamer Identities

open access: yes, 2016
The term ‘gamer identity’ is hotly contested, and certainly not understood as a broadly accepted term. From the outdated stereotype of white, heterosexual, teenage boys playing Nintendo in their parents’ basement to the equally contested proclamation ...
de Wildt, Lars   +8 more
core   +2 more sources

Start-up scheme for converter station of MMC-HVDC based on single-clamp sub-module using in grid black start

open access: yesThe Journal of Engineering, 2018
Single-clamp sub-module (SCSM) combining the cost and technological advantages has become one of the next modular multilevel converter (MMC) sub-module topologies in response to DC fault aspect.
ChaoLiang Wang   +4 more
doaj   +1 more source

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