Results 81 to 90 of about 491,360 (284)
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
System development issues concerning integration of wind generation in Great Britain [PDF]
, 2009 The European Union has committed itself to sourcing 20% of its energy from renewables by 2020. Britain's excellent wind resource is expected to make a significant contribution to this target, not least from Scotland and the north of England.
Bell, K.R.W.
core
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Overcoming barriers to electrical energy storage: Comparing California and Europe [PDF]
, 2016 Multiple market drivers suggest that electrical energy storage (EES) systems are going to be essential for future power systems within the next decade.
Castellano, F., Pollitt, M. G.
core +2 more sources
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Proposal for the Procedure of Supply Restoring for Power Plant Teplárny Brno Auxiliary System after Extensive System Fault in PS [PDF]
, 2015 Tato práce se zabývá problematikou obnovy provozu Špitálka společnosti Teplárny Brno, a. s., po rozsáhlé systémové poruše typu „blackout“. Práce řeší start ze tmy provozu Špitálka TB podáním napětí z vodní elektrárny Vír I, navrhuje metodický postup ...
Jára, Jaroslav
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Shanghai Jiaotong Daxue xuebaoWith the increasing proportion of new energy in the power grid, photovoltaic microgrids equipped with large-capacity distributed energy storage have the potential to support the black start of thermal power plants.
ZHOU Xia, CHEN Wenjian, DAI Jianfeng, XIE Xiangpeng
doaj +1 more source
The Healing Touch: Tools and Challenges for Smart Grid Restoration [PDF]
, 2014 Major electric power disturbances can be triggered by storms, heat waves, solar flares, and many other sources, but all have their roots in the mechanical, cyber, and human vulnerabilities of existing power grids.
Hou, Y, Liu, C, Liu, S, Podmore, R
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source