Results 91 to 100 of about 9,606,964 (338)

How to Un-Supplement a Tsunami of Fiscal Proportions: An Examination of the Supplemental Appropriations Process [PDF]

open access: yes, 2009
Article I § 9 clause 7 of the United States Constitution makes it clear that “No Money shall be drawn from the Treasury, but in Consequence of Appropriations made by Law.” This single sentence provides Congress with the sole legislative authority to ...
Black, Jonathan
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Impedimentos da cor: mulatos no Brasil e em Portugal c. 1640-1750 The meaning of colors: mulatos and blacks in Brazil and Portugal c. 1640-1750

open access: yesVaria História, 2012
O presente artigo pretende analisar vários testemunhos a partir de duas questões. Inicialmente investiga a hierarquia entre as cores da pele, a dicotomia entre branco/nobre e negro/vil.
Ronald Raminelli
doaj  

STRATIGRAPHY OF THE UPPER PLEISTOCENE-HOLOCENE DEPOSITS OF THE BLACK AND AZOV SEAS

open access: yesГеологія і корисні копалини Світового океану, 2021
The results of comparison of stratigraphic sections of Upper Pleistocene-Holocene sediments of the Black and Azov Seas, the main stratotypic areas: the Kerch Strait, the northwestern shelf of the Black Sea, the Azov Sea and its southern shores.
Inozemtsev Yu.I.
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Effectively Preserving Philadelphia's Workforce Housing Stock [PDF]

open access: yes, 2009
Compares home repair costs with the consequences of residential abandonment. Calls for expanded Basic Systems Repair Programs and deferred loans to help those unable to afford repairs, code enforcement, targeted and integrated funding, and ...
Karen Black
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

SOCIAL CAPITAL, SUPPORT NETWORKS AND BLACK ELDERLY PERSONS

open access: yesSocial Work/Maatskaplike Werk, 2007
The Department of Social Services and Poverty Alleviation in the Western Cape sees itself as the lead Department for social capital formation. (Department of Social Services and Poverty Alleviation, 2005:5).
Francis Howes
doaj   +1 more source

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