Results 101 to 110 of about 5,212,885 (344)

Black is the new black [PDF]

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 2018
Dawn S, Hui, Richard, Lee
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Impedimentos da cor: mulatos no Brasil e em Portugal c. 1640-1750 The meaning of colors: mulatos and blacks in Brazil and Portugal c. 1640-1750

open access: yesVaria História, 2012
O presente artigo pretende analisar vários testemunhos a partir de duas questões. Inicialmente investiga a hierarquia entre as cores da pele, a dicotomia entre branco/nobre e negro/vil.
Ronald Raminelli
doaj  

STRATIGRAPHY OF THE UPPER PLEISTOCENE-HOLOCENE DEPOSITS OF THE BLACK AND AZOV SEAS

open access: yesГеологія і корисні копалини Світового океану, 2021
The results of comparison of stratigraphic sections of Upper Pleistocene-Holocene sediments of the Black and Azov Seas, the main stratotypic areas: the Kerch Strait, the northwestern shelf of the Black Sea, the Azov Sea and its southern shores.
Inozemtsev Yu.I.
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Black Hills landscape

open access: yes
Black Hills landscape view with a line of electric poles visible. In envelope: "Black Hills Timber Stands.
Ferweda, C. E.
core   +4 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

GW151226: Observation of Gravitational Waves from a 22-Solar-Mass Binary Black Hole Coalescence

open access: yes, 2016
We report the observation of a gravitational-wave signal produced by the coalescence of two stellar-mass black holes. The signal, GW151226, was observed by the twin detectors of the Laser Interferometer Gravitational-Wave Observatory (LIGO) on December ...
P. Groot   +299 more
semanticscholar   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

SOCIAL CAPITAL, SUPPORT NETWORKS AND BLACK ELDERLY PERSONS

open access: yesSocial Work/Maatskaplike Werk, 2007
The Department of Social Services and Poverty Alleviation in the Western Cape sees itself as the lead Department for social capital formation. (Department of Social Services and Poverty Alleviation, 2005:5).
Francis Howes
doaj   +1 more source

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