Results 91 to 100 of about 5,212,885 (344)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Dossier: Mapping Screen Heritage (Introduction)

open access: yesAlphaville: Journal of Film and Screen Media
Archives of film and media are being challenged, critiqued, and reimagined. The heritage that has been preserved and the knowledge production to which it contributes has typically reinforced systemic structural barriers and inequalities and privileged ...
Rinella Cere   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Inappropriate Left Ventricular Mass and Cardiovascular Disease Events and Mortality in Blacks: The Jackson Heart Study

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Left ventricular hypertrophy (LVH) is associated with an increased risk for cardiovascular disease (CVD) events and all‐cause mortality. Many individuals without LVH have a left ventricular mass that exceeds the level predicted by their sex ...
D. Edmund Anstey   +8 more
doaj   +1 more source

BCC presents Brown Sugar, eighty years of America's Black female superstars, a lecture and slide presentation by Donald Bogle

open access: yes, 2010
Flyer about Donald Bogle’s lecture (front); Ahmad Jamal and his Trio perform (back)Donald Bogle give lecture, “Brown Sugar: Eighty Years of America’s Black Female Superstars” (front); Homecoming concert featuring Ahmad Jamal and his Trio, sponsored by ...
Purdue University. Black Cultural Center
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Black Hills view

open access: yes, 1972
An aerial view of the Black Hills. In envelope: "Misc Scenery." Photo stamped: "Black Hills National Forest.
Ferweda, C. E.
core   +2 more sources

["Junior Black Academy vs Dallas" documentary video]

open access: yes, 1984
Video footage provided by The Black Academy of Arts and Letters recorded during a news section on the conflict between the city of Dallas and the academy over a new location in the developing Dallas arts district.
Black Horizons
core  

Are Black Holes Black Bodies?

open access: yesNuclear Physics B, 1986
Abstract We give a new derivation for the properties of radiation appearing to an observer bounded in a space-time domain that has a horizon; this includes the Rindler case (constant accelerating frame) and the Schwarzschild solution (black hole). Because of the global nature of the quantum state, which inevitably extends to space beyond the horizon,
openaire   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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