Results 41 to 50 of about 4,420,718 (306)

Knowledgeable, aware / interested: Young black women's perceptions of pre-exposure prophylaxis

open access: yesFrontiers in Reproductive Health, 2022
PurposeHIV in the United States disproportionately affects young Black women. Pre-exposure prophylaxis (PrEP) is an effective HIV prevention option that has the potential to reduce HIV incidence among HIV-vulnerable populations.
Sadia Haider   +7 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

‘Is It Entrepreneurship, or Is It Survival?’: Gender, Community, and Innovation in Boston’s Black Immigrant Micro-Enterprise Spaces

open access: yesSocieties, 2017
Micro-enterprises are typically classified as businesses with fewer than six employees and very small amounts of financial capital. Focusing on black immigrant women’s micro-entrepreneurial ventures in Boston, this paper explores how non-economic forms ...
Ping-Ann Addo
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Building Bear Fences for Your Apiary

open access: yesEDIS, 2021
The American black bear is beloved, but it is also the most damaging vertebrate pest of honey bee apiaries in North America. That is in part because bears and beekeepers often share the same home territory.
Kimberly K. Post, Cameron Jack
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Travelling Ideologies: A Story of Whiteness

open access: yesLinguaculture, 2015
Prompted by the observations of a European scholar in African-American studies living in South-East Asia, this article addresses the ideological value of whiteness with a view to understanding its apparently global aesthetic fascination and societal ...
Cogeanu Oana
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Techno-Ethno Genealogy: An African Ancestry Narrative in the Digital Age

open access: yesGenealogy, 2018
This article explores ways in which advances in genetic testing have both facilitated and democratized genealogical research for individuals in search of their “roots” or ethnic heritage.
Mario Chandler
doaj   +1 more source

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