Results 61 to 70 of about 5,212,885 (344)

A Relationship between Nuclear Black Hole Mass and Galaxy Velocity Dispersion [PDF]

open access: yes, 2000
We describe a correlation between the mass Mbh of a galaxy's central black hole and the luminosity-weighted line-of-sight velocity dispersion σe within the half-light radius.
K. Gebhardt   +14 more
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

EIN NEUES LEBEN: ROT-SCHWARZ ROT

open access: yesAnadolu Üniversitesi Eğitim Fakültesi dergisi, 2018
Es waren gerade mal zwei Jahre, dass ich in diese Stadt kam. Als ich an dem Busbahnhof in einer Zeit ankam, in der die Sterne trödelten, hatte ich bereits gespürt, dass auch mein Schicksal hier genauso wie die dunkle Nacht sein würde, dunkel wie Teer ...
Gülcan Çakır
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Binge Drinking among Economically Disadvantaged African American Older Adults with Diabetes

open access: yesBehavioral Sciences, 2019
Purpose. This study investigated the effect of demographic, socioeconomic, and psychological factors as well as the role of health determinants on alcohol consumption and binge drinking among economically disadvantaged African American older adults with ...
Shervin Assari   +3 more
doaj   +1 more source

Knowledgeable, aware / interested: Young black women's perceptions of pre-exposure prophylaxis

open access: yesFrontiers in Reproductive Health, 2022
PurposeHIV in the United States disproportionately affects young Black women. Pre-exposure prophylaxis (PrEP) is an effective HIV prevention option that has the potential to reduce HIV incidence among HIV-vulnerable populations.
Sadia Haider   +7 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

‘Is It Entrepreneurship, or Is It Survival?’: Gender, Community, and Innovation in Boston’s Black Immigrant Micro-Enterprise Spaces

open access: yesSocieties, 2017
Micro-enterprises are typically classified as businesses with fewer than six employees and very small amounts of financial capital. Focusing on black immigrant women’s micro-entrepreneurial ventures in Boston, this paper explores how non-economic forms ...
Ping-Ann Addo
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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